Bioengineering is currently witnessing remarkable evolution through advancements in nanogenerator technologies, which hold great promise in the domains of human-machine interactions, personalized healthcare, and sustainable energy solutions. Nanogenerators offer novel approaches for converting mechanical energy derived from bodily movements—including human motion, cardiac cycles, and respiratory processes—into usable electrical energy. These devices have already demonstrated potential as critical components within wearable and implantable systems, providing autonomous energy generation, continuous physiological monitoring, and improved communication interfaces between biological systems and digital devices. Nevertheless, efficiency optimization, device durability, integration techniques, and ensuring biocompatibility remain pivotal obstacles in fully realizing their translational benefits, highlighting critical gaps necessitating deeper research exploration.

This Research Topic aims to resolve outstanding issues and investigate the unmet demands in nanogenerator technology within bioengineering applications, emphasizing advances in efficiency enhancement, biocompatibility, integration methodology, and practical implementation strategies. Key objectives include elucidating strategies for improved human-machine interaction, developing effective self-powered wearable and implantable health monitoring systems, and enabling advancements in personalized medicine for diagnosis, treatment, and disease prevention. We encourage researchers to submit findings that provide in-depth analyses, experimental outcomes, theoretical insights, and innovative designs in these emerging areas.

To gather further insights within the context of nanogenerators applied to bioengineering, this Research Topic will specifically encompass studies investigating the functionality, design, and integration of these technologies. We welcome articles addressing, but not limited to, the following themes:

• Enhanced interfaces for human-machine interactions such as body movement tracking, tactile feedback, and voice-responsive systems
• Novel techniques for biomechanical energy harvesting, integrating approaches like footstep tracking, pressure-induced, vibration-driven, ultrasonic, and textile-based nanogenerators
• Design, development, and assessment of implantable nanogenerators tailored for long-term integration in biological environments
• Nanogenerator technologies for accurate and continuous monitoring of physiological parameters, including cardiac activity, respiration dynamics, blood pressure, and pulse rate
• Applications of nanogenerator devices for injury prevention and early detection of neurological and orthopedic conditions
• Innovations in biomedical imaging approaches through nanogenerator-powered ultrasound techniques
• Applications and innovations of nanogenerators in animal and plant bioengineering systems

Accepted manuscript types include Original Research, Review, Mini Review, Perspective, and Opinion articles.

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Nanogenerator Technologies bridging Bioengineering and Human-Machine Integration

Topic Coordinator