Research Topic

Exposure to Endocrine-Disrupting Chemicals and Cardiometabolic Disease: A Developmental Origins Approach

About this Research Topic

Exposure to endocrine disrupting chemical (EDCs), such as bisphenol A and phthalates, have been implicated in development of cardiometabolic diseases, like type 2 diabetes and metabolic syndrome. To date, few studies have considered the interactive effects of EDC exposure during multiple vulnerable developmental life stages, and little is known regarding the underlying biological mechanisms that link EDCs to adverse metabolic health.

This Research Topic call welcomes human and animal studies exploring the effects of exposure to individual EDCs and/or EDC mixtures during single or multiple sensitive periods throughout the life course (e.g., the gestational period, infancy, early childhood, peripuberty, pregnancy, perimenopause) on cardiometabolic health. This call also welcomes studies interrogating mechanisms that mediate the relationship between the EDCs and metabolic health (e.g., epigenetics, proteomics, metabolomics, microbiome, interference with hormone receptor activity).


Keywords: Endocrine disrupting chemicals, developmental origins of health and disease, metabolic risk


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Exposure to endocrine disrupting chemical (EDCs), such as bisphenol A and phthalates, have been implicated in development of cardiometabolic diseases, like type 2 diabetes and metabolic syndrome. To date, few studies have considered the interactive effects of EDC exposure during multiple vulnerable developmental life stages, and little is known regarding the underlying biological mechanisms that link EDCs to adverse metabolic health.

This Research Topic call welcomes human and animal studies exploring the effects of exposure to individual EDCs and/or EDC mixtures during single or multiple sensitive periods throughout the life course (e.g., the gestational period, infancy, early childhood, peripuberty, pregnancy, perimenopause) on cardiometabolic health. This call also welcomes studies interrogating mechanisms that mediate the relationship between the EDCs and metabolic health (e.g., epigenetics, proteomics, metabolomics, microbiome, interference with hormone receptor activity).


Keywords: Endocrine disrupting chemicals, developmental origins of health and disease, metabolic risk


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

16 April 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

Loading..

Topic Editors

Loading..

Submission Deadlines

16 April 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..

Comments

Loading..

Add a comment

Add comment
Back to top