Data-driven research for precision population care is an emerging field at the intersection of big data, healthcare delivery, and population health. In recent years, the availability of large-scale datasets—such as national health records, disease registries, and extensive population cohorts, has transformed how researchers understand the complex factors influencing health outcomes. Despite the abundance of data, significant challenges remain in harnessing this information to accurately predict disease risks and develop personalized interventions for diverse and vulnerable populations. Current discussions center on the need for improved methodologies and frameworks that address health disparities and integrate social and behavioral determinants into risk models.

This Research Topic aims to explore innovative data-driven methods for enhancing precision in population care. By focusing on the development and application of robust models and analytical tools, we aim to uncover mechanisms underpinning health disparities and improve the predictive accuracy of disease risk models. Key objectives include clarifying the role of social and behavioral determinants in health outcomes and advancing public health practice through the application of sophisticated methodologies. We invite manuscripts that address the challenges of utilizing large datasets, develop and validate clinical predictive models, and propose targeted strategies for precision-based prevention.

To gather further insights into how data-driven research can advance precision population care, we welcome articles addressing, but not limited to, the following themes:

• Original research utilizing large-scale population cohorts or real-world data.
• Investigation of social and behavioral determinants of health and their underlying mechanisms.
• Development, validation, and application of disease risk prediction models.
• Focus on health disparities and precision-based prevention across the life course or within specific vulnerable populations.
• Application of advanced methodologies to improve public health practice and support decision-making.

Are you interested in contributing a manuscript to this Research Topic?

Innovations in Precision Health: Data-Driven Research for Population Care