The increasing prevalence of asthma and obesity worldwide has highlighted an urgent need for in-depth research into their relationship. Substantial evidence now points to obesity not only escalating the risk of developing asthma but also exacerbating its severity. This correlation potentially arises from shared inflammatory processes and immune dysfunction. Importantly, metabolic disturbances typical of obesity could also contribute to the structural changes seen in asthmatic airways, warranting further investigation into these complex biological interactions.The primary objectives of this Research Topic are to dissect the links between asthma and obesity, elucidate underlying pathophysiological mechanisms, and foster the development of effective interventions for management and prevention. By integrating findings from diverse studies, including epidemiological, clinical, and mechanistic research, this topic seeks to advance our understanding of how obesity modifies asthma pathogenesis and outcomes.In pursuit of these goals, the research scope specifically includes:• Epidemiological evaluations of asthma incidence among obese populations.• Analysis of inflammation and immune responses connecting obesity to asthma.• Studies on how obesity-related metabolic dysfunction influences airway remodeling in asthma.• Examination of the effects of weight management on asthma control in obese individuals.• Investigation into early-life obesity interventions and their potential to impact asthma development in later stages.This Research Topic encourages submissions across a spectrum of article types to facilitate a comprehensive exploration of these themes, thereby driving forward the collaborative efforts needed to tackle these intertwined public health challenges.
The increasing prevalence of asthma and obesity worldwide has highlighted an urgent need for in-depth research into their relationship. Substantial evidence now points to obesity not only escalating the risk of developing asthma but also exacerbating its severity. This correlation potentially arises from shared inflammatory processes and immune dysfunction. Importantly, metabolic disturbances typical of obesity could also contribute to the structural changes seen in asthmatic airways, warranting further investigation into these complex biological interactions.The primary objectives of this Research Topic are to dissect the links between asthma and obesity, elucidate underlying pathophysiological mechanisms, and foster the development of effective interventions for management and prevention. By integrating findings from diverse studies, including epidemiological, clinical, and mechanistic research, this topic seeks to advance our understanding of how obesity modifies asthma pathogenesis and outcomes.In pursuit of these goals, the research scope specifically includes:• Epidemiological evaluations of asthma incidence among obese populations.• Analysis of inflammation and immune responses connecting obesity to asthma.• Studies on how obesity-related metabolic dysfunction influences airway remodeling in asthma.• Examination of the effects of weight management on asthma control in obese individuals.• Investigation into early-life obesity interventions and their potential to impact asthma development in later stages.This Research Topic encourages submissions across a spectrum of article types to facilitate a comprehensive exploration of these themes, thereby driving forward the collaborative efforts needed to tackle these intertwined public health challenges.