Upper urinary tract reconstruction (UUTR) and the management of ureteral strictures are crucial areas in urology that significantly impact patient health and quality of life. Ureteral strictures can develop from various causes, such as surgery, injury, infection, malignancy, or congenital issues. They can lead to complications like obstructive nephropathy and recurrent infections, which, if neglected, may escalate to renal failure. Developing a thorough understanding of the formation mechanisms, enhancing diagnostic procedures, and discovering innovative treatment options remain essential for improving patient outcomes.

This Research Topic aims to illuminate recent advancements in diagnosing and treating ureteral strictures and reconstructive practices for the upper urinary tract. We seek to explore the latest advancements, including pathological understandings, innovations in surgical techniques, and cutting-edge therapies, all of which are pivotal in evolving the standard of care for affected individuals.

To gather further insights into the complexities of ureteral strictures and upper urinary tract reconstruction, we welcome articles addressing, but not limited to, the following themes:
•Molecular and cellular mechanisms leading to ureteral stricture formation, with a focus on inflammation, fibrosis, and muscle remodeling.
•Innovations in imaging and biomarkers for early detection and progress monitoring of ureteral strictures.
•Latest advancements in surgical methods, including minimally invasive and robotic surgeries, and graft or flap applications for reconstruction.
•Application of regenerative medicine, tissue engineering, and scaffolds in ureteral healing and function restoration.
•Exploration of new pharmacological treatments targeting fibrosis and scarring, including antifibrotic agents and gene therapies.
•Utilization of 3D printing in tailored surgical planning, patient-specific models, and the development of ureteral scaffolds.
•Strategies for optimizing post-operative care to enhance outcomes and minimize recurrence or complications.

Are you interested in contributing a manuscript to this Research Topic?

Innovations in Treating Ureteral Strictures and Upper Urinary Tract Issues