Biosensors and biomolecular electronics represent powerful tools in biomedical diagnostics, healthcare monitoring, and personalized medicine. Recent advancements in technology, including artificial intelligence (AI), blockchain, the Internet of Things (IoT), advanced data analytics, and distributed networks, have significantly transformed the biosensing landscape. Despite notable progress, current challenges remain with respect to biosensor accuracy, sensitivity, real-time capability, data security, and efficient integration of emerging technologies. Latest studies emphasize achievements in continuous health monitoring through smart wearable sensors integrated with real-time predictive analytics, point-of-care diagnostic solutions, and secure health data management driven by blockchain and distributed ledger innovations. Nevertheless, gaps persist related to robust miniaturization, biocompatibility, seamless technology integration, and addressing ethical and regulatory concerns comprehensively.

This Research Topic aims to present innovative research exploring the integration of biosensors and biomolecular electronics with cutting-edge emerging technologies for enhanced biomedical applications. Submissions should provide solutions to current technological limitations, highlight novel transduction mechanisms, address integration challenges, or introduce pioneering frameworks. Original research should answer critical questions on improved biosensor accuracy, sensor biocompatibility, secure data transmission methods, as well as investigate hypotheses regarding advancements made through converging technologies affecting the future landscape of medical diagnostics and personalized healthcare.

To gather further insights within the intersection of biosensing technologies with AI, blockchain, IoT, and data analytics, we welcome articles addressing, but not limited to, the following themes:

• Advanced biosensor miniaturization for point-of-care diagnostics.
• AI-driven predictive analytics in biosensing applications.
• Integration strategies of blockchain technology for secure, transparent health data management.
• Innovative biomolecular transduction mechanisms enhancing sensor accuracy and sensitivity.
• Real-time IoT-enabled biosensing platforms for continuous health monitoring.
• Ethical considerations and privacy implications in biosensor and biomolecular electronic implementations.
• Regulatory frameworks influencing innovation and integration in emerging sensor technologies.

We welcome Original Research articles, Reviews, Perspectives, Case Studies, and Technology Reports to contribute comprehensive discussions relevant to this Research Topic.

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Integration of Next-Generation Technologies with Biosensors for Advanced Diagnostics and Personalized Medicine