About this Research Topic
This Research Topic invites clinical science, basic science, and review articles that address:
• Sleep metabolic physiology: How does healthy sleep affect whole-body, tissue, or cellular metabolism? What are the effects of variables such as age, sex, diet, obesity, activity, or exercise on metabolic function during sleep? Outcomes may include energy expenditure, weight gain, appetite, substrate utilization, hormones, genetic/epigenetics, and signaling pathways.
• Sleep-related metabolic pathology: How do sleep disorders affect whole-body, tissue, or cellular metabolism? For example, what are the metabolic consequences of altered circadian rhythm, long/short sleep duration, insomnia, sleep apnea, or restless leg syndrome? What are the underlying mechanisms of these impacts? As above, outcomes may include energy expenditure, weight gain, appetite, substrate utilization, hormones, genetic/epigenetics, and signaling pathways.
• Sleep as a window into endocrine disease: What are the impacts of endocrine disorders such as diabetes, Cushing’s syndrome, acromegaly, thyroid dysfunction, or eating disorders on sleep quality or architecture? Can sleep be useful for assessing metabolic health?
• Therapeutic interventions to improve metabolic health through sleep: Are there known or novel pathways that can be targeted during sleep to improve overall cardio-metabolic health?
Keywords: Sleep, metabolism, diabetes, apnea, circadian
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.