Cytokine and growth factor signaling are fundamental to regulating various physiological processes, such as immune responses, cell growth, and tissue repair. These signaling networks are finely tuned to maintain cellular homeostasis and adapt to external and internal changes. Dysfunction in these pathways can lead to several pathological conditions, including cancers, inflammatory disorders, and immune system dysfunctions, highlighting the importance of understanding the regulation mechanisms underpinning these pathways.

This Research Topic aims to investigate the complex regulatory networks of cytokine and growth factor signaling to better understand their role in maintaining health and contributing to disease. It seeks to reveal the molecular details of how these pathways are regulated, how changes in their activity can lead to disease, and how they can be manipulated for therapeutic purposes. Specific questions include the impact of genetic variations, environmental factors, and therapeutic interventions on the signaling dynamics.

To collect comprehensive data on this subject, the Research Topic will encompass a range of themes, including:

Mechanisms of cytokine signaling in immune system regulation.

Growth factor signaling roles in cell proliferation and healing.

Cross-talk between cytokine and growth factor pathways in cancer.

Innovative treatments targeting cytokine and growth factor dysregulation.

Epigenetic modifications affecting cytokine and growth factor signaling.

The interrelation between infectious diseases and cytokine responses.

Contributions will include original research, comprehensive reviews, and case studies that address these themes. This collection aims not only to synthesize the current understanding of cytokine and growth factor signaling but also to push the boundaries of what is known, opening new avenues for research and therapy in the field.

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Regulation of Cytokine and Growth Factor Signaling in Health and Disease