This Research Topic is the third volume of the Research Topic "Bridging the Gap: An Interdisciplinary Perspective on Ketamine in Psychiatric Disorders". Please see the first volume here and our second volume here.

Ketamine and its enantiomers (R, S) represent pharmacologically novel treatment avenues for individuals with treatment-resistant depression, exerting rapid and robust antidepressant and anti-suicidal effects that provide new hope to affected persons.

Frontiers in Psychiatry is working to promote integrative multidimensional psychiatry research through an interdisciplinary approach to mental health. This Research Topic on Ketamine aims to promote the collaboration of multidisciplinary teams from a variety of professional disciplines to foster high standards of comprehensive care, research, and best practice in psychiatry to attract high-quality original research papers, comprehensive review articles, and opinion papers. The shared implications of the studies will:

a) Provide an overview of recent advances in research on Ketamine and its enantiomers (R, S) with psychiatric disorders.
b) Help identify comprehensive intervention strategies to enhance mental health outcomes.
c) Expand awareness around the use of Ketamine and its enantiomers with multiple implications for psychiatric care and practice.

We welcome original research and review articles of both preclinical and clinical studies on but not limited to:

- The impact of Ketamine on suicidal symptoms in individuals with mood disorders.
- The impact of Ketamine in adult and child populations with major depressive disorder (MDD).
- Ketamine in depression with psychotic symptoms.
- Ketamine in bipolar depression, complex trauma, anxiety disorders, and personality disorders.
- Ketamine as a long-term treatment: outcomes and adverse effects
- Case reports and/or case series regarding Ketamine administration in the clinical routine.
- Outcome studies with the implementation of Ketamine assisted psychotherapy.
- The administration of Ketamine beyond the diagnosis of MDD
- The neurobiological underpinnings of psychiatric treatment with Ketamine.
- Ketamine-related novel treatments for depression.

Are you interested in contributing a manuscript to this Research Topic?

Bridging the Gap: An Interdisciplinary Perspective on Ketamine in Psychiatric Disorders - Volume III