Given the success of Volume I of this Research Topic, and how rapid the subject area is evolving, we are pleased to announce the update of Fractures and Deformities of the Extremities in Children and Adolescents: Etiology, Diagnosis, and Treatment Volume II. This is a rapidly evolving field, encompassing a heterogeneous group of conditions related to the fractures of the extremities and deformities in children and adolescents. These conditions arise from a variety of diseases, affecting areas from the shoulder joint to the foot. While some are caused by known trauma, others may be a consequence of developmental disorders or mutations in various genes. The presenting symptoms and signs may vary from cosmetic findings to the dysfunction of the limb, except fractures.

Despite advances in diagnosis and treatment, there is still a lack of understanding of the etiology and pathogenesis of many of these conditions. Furthermore, there are ongoing challenges in the diagnosis and treatment of rare or complex fractures and deformities of the extremities. To address these challenges, the present Research Topic aims to call for manuscripts describing unique cases with follow-up and treatment, as well as studies examining the outcome and prognosis. This will increase awareness of these conditions and lead to improved diagnosis and treatment for children and adolescents.

The scope of this Research Topic includes a broad range of topics related to the fractures of the extremities and deformities in children and adolescents, including the following specific subthemes:
• Mechanisms and genetic background of rare or complex fractures of the extremities
• Treatment outcomes and challenges in rare or complex fractures of the extremities
• Etiology and genetic background of the extremity deformities
• Challenges in the diagnosis and treatment of the extremity deformities from birth to adolescence
• Novel treatment options for fractures and deformities of the extremities
• Natural outcomes and progression of fractures and deformities in the extremities
• Gene therapy for deformities of the extremities caused by congenital diseases

We welcome original research articles, reviews, and case reports that describe the unique etiology, clinical presentation, and outcome of children and adolescents with fractures or deformities of the extremities.

Are you interested in contributing a manuscript to this Research Topic?

Fractures and Deformities of the Extremities in Children and Adolescents: Etiology, Diagnosis, and Treatment: 2025