Congenital lung diseases in children, including congenital airway malformations (CPAM), bronchopulmonary isolation (BPS), congenital hyperdilation of the lung lobes, etc., are a rare but clinically significant developmental abnormality. These conditions are usually determined prenatal through routine fetal ultrasound examinations. Their early detection leads to increasingly aggressive prenatal counseling and even uterine intervention. After birth, manifestations range from asymptomatic accidental discovery to life-threatening respiratory distress, usually requiring timely surgical or medical intervention.

The latest advancements in gene sequencing and molecular biology have begun to reveal the developmental pathways and genetic mutations of congenital lung abnormalities, although there is still much to be explored. Meanwhile, surgical innovations including minimally invasive thoracoscopic techniques and lung-preserving surgical strategies have changed the treatment landscape and improved perioperative efficacy and long-term lung function. However, questions regarding the optimal surgical timing, long-term respiratory health and psychosocial impacts have still not been adequately answered. This special issue aims to integrate the latest multidisciplinary insights, including the diagnosis, pathogenesis, management and longitudinal outcomes of congenital lung diseases in children.

This special issue seeks to address the full clinical and scientific continuum of congenital lung diseases in children. Our goal is to promote interdisciplinary cooperation and highlight innovations that contribute to early diagnosis, more effective treatment and better long-term management. By bringing together leading pediatric surgeons, neonatologists, radiologists, geneticists and basic scientists, this issue will provide a comprehensive overview of the current state and future direction of this field. Submissions that combine clinical experience with scientific discoveries are particularly encouraged.

Authors are invited to submit original research, reviews, or case reports that address, but are not limited to, the following topics:
• Epidemiology of Congenital Lung Diseases in Children
• Prenatal Diagnosis and Intervention for Congenital Pulmonary Diseases in Children
• Etiology and Molecular Mechanisms of Congenital Pulmonary Diseases in Children
• Advances and Strategies in the Treatment of Congenital Pulmonary Diseases in Children
• Long-term Management and Quality of Life in Children with Congenital Lung Diseases
• Case Studies and Insights into Rare Congenital Lung Diseases in Children

We welcome multidisciplinary perspectives and encourage submissions that bridge basic science and clinical practice.

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Congenital Lung Disease in Children