In the field of gynecological health, growing attention is being directed toward the intricate connections between the vaginal, urinary, and intestinal microbiomes and their role in various diseases. Recent studies indicate that these microbial communities could be essential in developing new preventive and therapeutic approaches for conditions unique to women. While significant progress has been made, there remains a notable gap in understanding specific microbial patterns associated with particular conditions and their direct impact on health outcomes.

This Research Topic aims to transform our understanding of gynecological diseases by emphasizing the pivotal role of the microbiome in women's health. By identifying microbial signatures associated with various conditions, submissions should propose effective intervention strategies, including probiotics and personalized therapies, to restore microbial balance. The findings are expected to inform clinical practices and guide the development of innovative therapeutic approaches, ultimately enhancing the quality of life for women affected by these conditions. We encourage the use of advanced DNA sequencing and bioinformatics to characterize and analyze the microbiomes in relevant samples. Research should aim to identify specific microbial patterns linked to each condition and explore potential interactions between different microbiomes.

We invite researchers to contribute to an exciting exploration of the human microbiome's essential role in gynecological health. This research topic seeks to delve into the intricate relationships between the vaginal, urinary, and intestinal microbiomes and a spectrum of gynecological conditions. Our aim is to uncover how these microbial communities impact women's health and contribute to various pathologies.

To gather further insights into the microbiome's role in women's health, we welcome articles addressing, but not limited to, the following themes:

• Urinary Tract Infections and Overactive Bladder: We are interested in studies that investigate the urinary microbiome's composition in women experiencing recurrent urinary tract infections and overactive bladder. Research should focus on how microbial imbalances may influence the development and persistence of these conditions.

• Stress and Mixed Urinary Incontinence: Submissions should explore the microbiome's role in stress and mixed urinary incontinence, examining how changes in microbial populations can affect pelvic floor functionality and urinary tract health.

• Surgical Interventions: Mesh and Slings: We welcome research on the microbiome's impact on surgical outcomes, particularly regarding the use of mesh for genital prolapse and slings for urinary incontinence. Studies should assess how microbial factors may affect recovery and long-term success.

• Cervical Dysplasia and Gynecological Cancers: Contributions should investigate the association between the vaginal microbiome and the onset of cervical dysplasia, endometrial cancer, and breast cancer, focusing on microbial alterations that may drive carcinogenesis.

• Endometriosis and Uterine Leiomyoma: We seek research analyzing the microbiome in women with endometriosis and uterine leiomyoma, aiming to understand the connection between microbial imbalances, inflammation, and these conditions.

• Endometrial Polyps and Infertility: Studies should explore the microbiome's influence on endometrial polyp formation and infertility, particularly how microbial communities affect endometrial receptivity and embryo implantation.

With the application of advanced genomic techniques like DNA sequencing and bioinformatics, contributions to this topic will aid in unveiling critical microbial dynamics, providing a cornerstone for future women-centric health interventions.

Are you interested in contributing a manuscript to this Research Topic?

The Influence of Vaginal, Urinary, and Intestinal Microbiomes on Gynecological Diseases