Biofabrication has rapidly emerged as a cornerstone of modern tissue engineering, regenerative medicine, and biomanufacturing. As the field matures, it continues to evolve through the contributions of a dynamic new generation of researchers who are pushing the boundaries of what is possible. These early-career scientists are pioneering innovative techniques in areas such as 4D biofabrication, organ-on-chip platforms, advanced bioprinting, and smart biomaterials. Their work is not only reshaping our fundamental understanding but is also translating into practical biomedical applications. Recognizing and amplifying the voices of these rising talents is crucial for sustaining momentum, fostering innovation, and shaping the future direction of biofabrication.

This Research Topic aims to highlight outstanding contributions from ‘rising stars’ who are internationally recognized as future leaders in the field of biofabrication. By curating a collection of cutting-edge studies from these invited authors, the Research Topic will provide a platform to showcase novel methodologies, transformative insights, and visionary perspectives that reflect the evolving landscape of the discipline.

The invited contributions will span a range of subfields—such as bioprinting technologies, responsive biomaterials, bioreactor systems, and computational modeling for tissue design—highlighting both foundational science and translational breakthroughs. Our goal is to celebrate scientific excellence, stimulate interdisciplinary dialogue, and spotlight fresh ideas that may redefine challenges and opportunities in biofabrication. This initiative will also provide a valuable point of reference for institutions, funding bodies, and collaborators seeking to engage with the next wave of scientific leadership.

This invitation-only Research Topic will feature contributions from early-career researchers (e.g., junior faculty, postdoctoral fellows, or independent group leaders within ~10 years of their PhD) who are making significant strides in the field of biofabrication. Submissions may include original research, or comprehensive reviews.

We welcome work across a broad spectrum of themes, including:

• Innovative bioprinting and microfabrication techniques
• Smart and bioresponsive material systems
• Dynamic tissue constructs and 4D biofabrication
• Biofabrication for disease modeling, organoids, or in vitro systems
• Computational tools for design, simulation, and control of biofabricated systems

Please note that this is an invitation-only Research Topic. Manuscripts submitted by non-invited authors will be processed as general submissions and will not be included in this Research Topic. All contributions will undergo peer review and must meet the journal’s standards for scientific rigor and impact.

Are you interested in contributing a manuscript to this Research Topic?

Biofabrication Breakthroughs from Early-Career Innovators