Oxidative stress, an imbalance between the production of reactive oxygen species (ROS) and the ability to neutralize them with antioxidants, significantly impacts animal health and disease development. It influences chronic conditions in animals, such as metabolic disorders, cardiovascular diseases, and age-related issues. This stress affects cells and tissues, making it a pivotal target for nutritional interventions in veterinary medicine.

Emerging research suggests that natural bioactive compounds from plants, fruits, vegetables, fungi, and marine organisms, known for their antioxidant, anti-inflammatory, and cytoprotective properties, could be beneficial in animal nutrition. These compounds may mitigate oxidative stress, enhancing overall health and disease resistance in animals.

This Research Topic explores advancements in applying natural bioactive compounds to improve animal health through oxidative stress management. We invite submissions detailing how these compounds enhance antioxidant defenses, reestablish cellular homeostasis, and influence pathways related to metabolism. Studies on bioavailability, novel delivery systems like nanotechnology, sustainable sourcing, and preclinical applications in animals are particularly welcome.

Topics of interest include:

• Mechanisms by which bioactive compounds modulate oxidative stress in animals.
• Bioavailability challenges and innovations for natural antioxidants in animal nutrition.
• Impact on gene expression and metabolic pathways.
• Formulation strategies like nanotechnology to improve efficacy in animals.
• Comparative studies demonstrating their therapeutic potential in animal health.

By addressing these areas, this Research Topic contributes to advancing animal nutrition and metabolism, emphasizing disease prevention and the development of dietary supplements and treatments.

Are you interested in contributing a manuscript to this Research Topic?

Bioactive Natural Compounds and Their Role in Oxidative Stress in Animals