This Research Topic is part of a series with New insights into neurodevelopmental biology and autistic spectrum disorders”.

This Research Topic aims to provide a comprehensive examination of the new developments in neurobiology and their implications for autism spectrum disorders. The primary objective is to probe into how various brain phenotypes, such as brain overgrowth and altered connectivity patterns, are linked to behavioral characteristics, developmental trajectories, and cognitive profiles in individuals with ASD. Further inquiry will explore familial patterns of ASD and their neurobiological underpinnings. By synthesizing results from the latest imaging studies and neurobiological frameworks, this topic seeks to unravel the nuanced relationship between brain development, neurobiology, and observable behavior, which may inform clinical practices.

To gather further insights into the complex dynamics of ASD and its neurodevelopmental aspects, we welcome articles addressing, but not limited to, the following themes:

• Neuroimaging studies and their implications for understanding ASD

• Relationship among neurobiological markers, cognitive profiles, and behavioral characteristics

• Evaluation of familial patterns and genetic predispositions in ASD

• Impact of environmental stressors, such as the COVID-19 pandemic, on neurodevelopment

• Modeling ASD using brain organoids and induced pluripotent stem cells (iPSCs) to explore neuronal differentiation, synaptic function, and gene expression

• Translational approaches from research findings to clinical interventions

We encourage submissions exploring the wide spectrum of neurodevelopmental biology and autism through various research methodologies and article types.

Are you interested in contributing a manuscript to this Research Topic?

New insights into neurodevelopmental biology and autism spectrum disorders, volume II