The inaugural challenge in the Pediatric Critical Care section addresses the theme of innovative sepsis management and post-discharge care for children in low-resource and developing settings. This vital topic explores groundbreaking advancements and seeks to address critical questions within the field. Our goal is to evaluate and advance context-appropriate, scalable interventions across the acute and recovery phases—integrating technology, community resources, and cross-sector collaboration—to improve survival, recovery, and quality-of-life outcomes for pediatric patients.

The Specialty Chief Editor invites insightful and bold contributions—whether clinical studies, theoretical analyses, or data-driven research—that can provide new perspectives and foster meaningful discussion around the following open questions:

• What adaptations to sepsis recognition and management protocols are most effective and feasible in low-resource pediatric settings?
• How can emerging technologies (e.g., point-of-care diagnostics, decision-support tools, telemedicine, remote monitoring) be pragmatically integrated into acute and post-discharge care?
• Which models of community-based follow-up and transitional care reduce relapse, readmissions, and post-discharge mortality?
• What cost-effective, scalable strategies can strengthen pediatric critical care pathways from admission through recovery?
• How do multidisciplinary and cross-sector collaborations improve implementation fidelity and outcomes across diverse contexts?
• What are the key barriers and facilitators— infrastructural, workforce, sociocultural, and policy-related—affecting uptake of evidence-based practices?
• How can health systems, policy, and capacity-building initiatives sustainably support pediatric sepsis care and post-discharge follow-up?
• Which implementation science frameworks best evaluate real-world effectiveness, equity, and sustainability of new interventions?

This Research Topic encourages contributions from members of the Pediatric Critical Care section Editorial Board. Accepted article types include Brief Research Report, Original Research, Review, Mini Review, and Perspective. We aim to deepen understanding and promote innovative solutions for pediatric sepsis management and post-discharge care in resource-limited environments.

Are you interested in contributing a manuscript to this Research Topic?

Editor Challenge in Pediatric Critical Care: Innovative Sepsis Management and Post-Discharge Care in Low-Resource Settings