The "Rising Stars in Drug Metabolism and Transport 2025/2026" highlights the groundbreaking work of early-career researchers who are making significant contributions to our understanding of drug metabolism and transport processes. This feature aims to showcase innovative research that bridges fundamental science and practical application, aligning with global health and innovation goals.

Led by our Chief Editors Prof. Jaime Kapitulnik and Prof. Petr Pavek, this Drug Metabolism and Transport section is dedicated to advancing knowledge in how drugs, endogenous compounds, and environmental chemicals are metabolized and transported in the body. This research is crucial for developing safer and more effective pharmacological therapies and for improving public health outcomes.

We welcome submissions that spans a diverse array of topics within drug metabolism and transport, including but not limited to:

- Innovative tools and technologies: Development of novel in vitro and in vivo methods for assessing drug metabolism and transport.
- Genetic insights: Exploration of genetic variability and polymorphisms influencing drug metabolism and transport efficiency.
- In vitro to in vivo extrapolations (IVIVE): Techniques that enhance the predictability of how in vitro findings translate to in vivo outcomes.
- Modeling for drug design: Advanced computational and mechanistic models of drug metabolism and transport supporting drug design.
- Regulatory mechanisms: Studies on the regulation of drug-metabolizing enzymes and transporters.
- Theoretical and mechanistic explorations: Deeper understanding of the biochemical and physiological foundations of drug metabolism and transport.

While the section excludes submissions focused solely on therapeutic interventions, it welcomes research relating to drug delivery systems—particularly those involving nanoparticle technology and cancer treatment—as long as they directly pertain to drug metabolism and transport processes.

This collection of outstanding research is poised to influence the future direction of the drug metabolism and transport field, providing critical insights to researchers, the pharmaceutical industry, policymakers, and the broader scientific community. The "Rising Stars" series not only celebrates individual accomplishments but also fosters a collaborative environment where cutting-edge scientific discoveries can flourish for the benefit of public health worldwide.

Are you interested in contributing a manuscript to this Research Topic?

Rising Stars in Drug Metabolism and Transport - Frontiers in Pharmacology 2025/2026