The SARS-CoV-2 virus has led to the worldwide outbreak of the twentieth century. Current knowledge on SARS-CoV-2 acute infection has dramatically increased. Three years after the main outbreak, the presence of long-lasting symptoms after the acute infection called long COVID or post-COVID-19 syndrome, affects millions of individuals worldwide. Increasing literature supports the presence of more than 100 potential symptoms after the acute phase of infection such as:

· extreme fatigue, dizziness, and insomnia

· depression and anxiety, memory and concentration impairments

· loss of smell or taste, tinnitus, and earaches

· chest pain, heart palpitations, tightness, muscle aches.

However, several gaps still are present in the identification, timeframe, mechanisms, and treatment strategies for the management of long-COVID.

This Research Topic aims to update the current understanding of long COVID in relation to the underlying mechanisms, classification, and potential treatment approaches. Identification of groups of individuals with long-COVID according to mechanisms or clinical symptomatology could lead to better treatment approaches.

We are pleased to invite you to this Research Topic “Updating Long COVID: Mechanisms, Risk Factors, and Treatment”. This Research Topic will focus on all these aspects of post-COVID-19 condition, a topic of emerging relevance due to the absence of an effective treatment. This is highly relevant since long-COVID is independent of the SARS-CoV-2 variant or the implementation of vaccination programs. We invite researchers/clinicians to submit original articles, systematic reviews, narrative reviews, meta-analyses, cohort and case-control studies related to identification or management of post-COVID subgroups to this Research Topic

Are you interested in contributing a manuscript to this Research Topic?

Updating Long COVID: Mechanisms, Risk Factors, and Treatment Volume III