Research Topic

Heart Valve Tissue Engineering: Are We Ready for Clinical Translation?

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About this Research Topic

The third decade of research into engineering a heart valve holds real potential: will tissue engineered valves emerge into the clinic as a viable substitute for diseased heart valves, for both the pediatric and the adult population? Great progress has been made over the years, ranging from what cell sources to use to novel biomaterials, from in vitro studies to pre-clinical animal models as well as novel technologies, such as minimally invasive implantation strategies using tissue engineered valves. Translation to the clinic seems to be at hand, but what final hurdles remain? Can we overcome these hurdles? And will all patients benefit from a tissue engineered valve substitute?

This Research Topic focuses on just that: What innovations brought us where we stand today and what promises does the future bring? It aims to unite the field of heart valve tissue engineering in one Research Topic that discusses this exciting field of research that is on the verge of the next decade of highly innovative research and technology development, working towards the ultimate goal of clinical application. This Research Topic will consist of contributions by leading groups in the world, flanked by high-quality open contributions from excellent scientists in the field. The first international conference of tissue engineered heart valves (ICTEHV) will be organized 18th of May 2018, and will serve as a kick off to open this Research Topic for contributions from across the field.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

The third decade of research into engineering a heart valve holds real potential: will tissue engineered valves emerge into the clinic as a viable substitute for diseased heart valves, for both the pediatric and the adult population? Great progress has been made over the years, ranging from what cell sources to use to novel biomaterials, from in vitro studies to pre-clinical animal models as well as novel technologies, such as minimally invasive implantation strategies using tissue engineered valves. Translation to the clinic seems to be at hand, but what final hurdles remain? Can we overcome these hurdles? And will all patients benefit from a tissue engineered valve substitute?

This Research Topic focuses on just that: What innovations brought us where we stand today and what promises does the future bring? It aims to unite the field of heart valve tissue engineering in one Research Topic that discusses this exciting field of research that is on the verge of the next decade of highly innovative research and technology development, working towards the ultimate goal of clinical application. This Research Topic will consist of contributions by leading groups in the world, flanked by high-quality open contributions from excellent scientists in the field. The first international conference of tissue engineered heart valves (ICTEHV) will be organized 18th of May 2018, and will serve as a kick off to open this Research Topic for contributions from across the field.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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