About this Research Topic
“Am not I/A fly like thee?/Or art thou not/A man like me?” (William Blake)
The XIX IDRC “Italian Drosophila Research Conference” took place 20-22nd June 2018 at the Department of Biology of the University of Padova, Padova, Italy. This meeting gathered Italian researchers who use Drosophila melanogaster as a model organism in their research.
Since the early years of the 20th century, when the history of Drosophila in biological research began, the fruit fly has played a key role in unravelling a broad range of biological processes.
Drosophila is a complex multicellular organism in which not only basic cell biology is studied, but also higher-order events such as the many aspects of development and behavior given that they parallel those in higher vertebrates. The experimental advantages of Drosophila as a model system greatly benefits from the close relationship between fruit fly and human genes: in fact, 75 percent of the genes that cause disease in humans have homologues in Drosophila. Moreover, the sophisticated assortments of genetic and molecular tools that have evolved for analysis of gene function in this organism are unique. These combined advantages have permitted research in Drosophila to make key advances in the understanding of fundamental molecular, cellular, developmental, and neurobiological processes.
This Research Topic’s aim is to provide a collection of articles based on the oral presentations, reports, and experimental outcomes related to the topics of the conference: “Modelling human cancers in Drosophila”, “Epigenetics and DNA damage response in Drosophila”, “Genome stability in Drosophila”, “Modelling neurodegenerative and mitochondrial disorders in Drosophila”, “Mechanisms of sleep regulation in Drosophila”, and “Circadian regulation in Drosophila”.
Participants of the conference are welcome to submit manuscripts that could be Original Research, Review (including Mini Reviews), Methods, Hypothesis & Theory, and General Commentary articles. This Research Topic is open to additional scientists working on the topics of the conference. All of the submitted manuscripts will be peer-reviewed.
Keywords: Drosophila melanogaster, model organism, genetics, physiology, behavior
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