About this Research Topic
Traumatic and chronic stressors can impact brain structure and function and are considered primary sources of risk for depression, anxiety, and other psychiatric disorders. Interestingly, the majority of individuals who encounter stressful life events do not develop untoward outcomes. As successful adaptation relies on an organism's effective response to environmental and homeostatic challenges, a greater understanding of the factors that promote resistance to the deleterious effects of stress is of great clinical relevance. This Research Topic focuses on advances in understanding how genetic and experiential factors mitigate the consequences of stressful events, and the neural mechanisms that mediate their effects. Additionally, this Research Topic seeks to highlight recent efforts to identify conditions during an initial stress experience that can alter an organism’s response to aversive events later in life. We welcome all research articles, review papers, brief communications, and commentary on topics related to stress resilience and that will serve to inform current clinical interventions for stress-related disorders.