Neuropeptide GPCRs in neuroendocrinology

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Editorial

04 April 2014

Neuropeptide GPCRs in Neuroendocrinology

Hubert Vaudry

and

Jae Young Seong

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9 citations

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2

Université de Rouen

Jae Young Seong

Korea University

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The human genome encompasses ˜ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic is to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that will illustrate the different facets of the studies currently conducted in this domain.

The human genome encompasses ˜ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic is to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that will illustrate the different facets of the studies currently conducted in this domain.

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Editors

Université de Rouen

Jae Young Seong

Korea University

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645,054 Total views

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Frontiers in Endocrinology

Neuroendocrine Science

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Frontiers in Neuroscience

Neuroendocrine Science

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