Research Topic

Molecular Mechanisms of Pathogen-Driven Infectious and Neoplastic Diseases

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Increasing evidence indicates that the crosstalk between infectious agents and host is far more complex and sophisticated than originally expected, with pathogens’ genes and RNAs playing an important role in disturbing the regulatory mechanisms of host cells. This intricate interaction may persist even in ...

Increasing evidence indicates that the crosstalk between infectious agents and host is far more complex and sophisticated than originally expected, with pathogens’ genes and RNAs playing an important role in disturbing the regulatory mechanisms of host cells. This intricate interaction may persist even in healthy individuals, as lurking pathogens’ encoded factors may be constantly produced and imbalance host cell homeostasis, eventually leading to chronic inflammation and/or cancer.

Research has been key to identify what cellular pathways may be altered and has provided successful strategies to reduce the incidence of infectious agents-driven diseases, human papilloma virus (HPV) vaccines being a very good example. Nevertheless, there is still a lot to unveil because of emerging pathogens and/or development of escape mechanisms by infectious agents. It is crucial to identify cellular targets of pathogens to both reduce the incidence of a disease and design novel tailored therapeutic approaches to achieve a better prognosis and quality of life.

The aim of this Research Topic is to collect and share novel information focusing on molecular mechanisms used by pathogens to contribute to infectious diseases and cancer. All types of manuscripts shedding light on this topic will be welcome, including research articles, brief reports, letters and review articles.


Keywords: Infectious agents, cancer, infectious diseases, pathogen-host interaction, cell defense evasion


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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