Molecular Mechanisms of Pathogen-Driven Infectious and Neoplastic Diseases

132.8K

views

127

authors

16

articles

Editorial

31 May 2021

Editorial: Molecular Mechanisms of Pathogen-Driven Infectious and Neoplastic Diseases

Giulia De Falco

,

Davide Gibellini

,

Pier Paolo Piccaluga

,

Paul G. Murray

and

Sam Mbulaiteye

1,740 views

1 citations

Editors

5

Giulia De Falco

Queen Mary University of London

Davide Gibellini

University of Verona

Pier Paolo Piccaluga

University of Bologna

Paul Gerard Murray

University of Birmingham

Sam Mbulaiteye

National Cancer Institute (NIH)

Impact

About

Increasing evidence indicates that the crosstalk between infectious agents and host is far more complex and sophisticated than originally expected, with pathogens’ genes and RNAs playing an important role in disturbing the regulatory mechanisms of host cells. This intricate interaction may persist even in healthy individuals, as lurking pathogens’ encoded factors may be constantly produced and imbalance host cell homeostasis, eventually leading to chronic inflammation and/or cancer.

Research has been key to identify what cellular pathways may be altered and has provided successful strategies to reduce the incidence of infectious agents-driven diseases, human papilloma virus (HPV) vaccines being a very good example. Nevertheless, there is still a lot to unveil because of emerging pathogens and/or development of escape mechanisms by infectious agents. It is crucial to identify cellular targets of pathogens to both reduce the incidence of a disease and design novel tailored therapeutic approaches to achieve a better prognosis and quality of life.

The aim of this Research Topic is to collect and share novel information focusing on molecular mechanisms used by pathogens to contribute to infectious diseases and cancer. All types of manuscripts shedding light on this topic will be welcome, including research articles, brief reports, letters and review articles.

Download ebook

PDF

EPUB

Share

Editors

Giulia De Falco

Queen Mary University of London

Davide Gibellini

University of Verona

Pier Paolo Piccaluga

University of Bologna

Paul Gerard Murray

University of Birmingham

Sam Mbulaiteye

National Cancer Institute (NIH)

Impact

132,803 Total views

103,040 Article views

27,729 Article downloads

2,034 Topic views

Published In

Frontiers in Cell and Developmental Biology

Molecular and Cellular Pathology

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Suggest a topic