Molecular Mechanisms of Pathogen-Driven Infectious and Neoplastic Diseases

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Editorial

31 May 2021

Editorial: Molecular Mechanisms of Pathogen-Driven Infectious and Neoplastic Diseases

Giulia De Falco

,

Davide Gibellini

,

Pier Paolo Piccaluga

,

Paul G. Murray

and

Sam Mbulaiteye

1,740 views

1 citations

Editors

5

Giulia De Falco

Queen Mary University of London

Davide Gibellini

University of Verona

Pier Paolo Piccaluga

University of Bologna

Paul Gerard Murray

University of Birmingham

Sam Mbulaiteye

National Cancer Institute (NIH)

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Increasing evidence indicates that the crosstalk between infectious agents and host is far more complex and sophisticated than originally expected, with pathogens’ genes and RNAs playing an important role in disturbing the regulatory mechanisms of host cells. This intricate interaction may persist even in healthy individuals, as lurking pathogens’ encoded factors may be constantly produced and imbalance host cell homeostasis, eventually leading to chronic inflammation and/or cancer.

Research has been key to identify what cellular pathways may be altered and has provided successful strategies to reduce the incidence of infectious agents-driven diseases, human papilloma virus (HPV) vaccines being a very good example. Nevertheless, there is still a lot to unveil because of emerging pathogens and/or development of escape mechanisms by infectious agents. It is crucial to identify cellular targets of pathogens to both reduce the incidence of a disease and design novel tailored therapeutic approaches to achieve a better prognosis and quality of life.

The aim of this Research Topic is to collect and share novel information focusing on molecular mechanisms used by pathogens to contribute to infectious diseases and cancer. All types of manuscripts shedding light on this topic will be welcome, including research articles, brief reports, letters and review articles.

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Editors

Giulia De Falco

Queen Mary University of London

Davide Gibellini

University of Verona

Pier Paolo Piccaluga

University of Bologna

Paul Gerard Murray

University of Birmingham

Sam Mbulaiteye

National Cancer Institute (NIH)

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104,022 Article views

27,942 Article downloads

2,039 Topic views

Published In

Frontiers in Cell and Developmental Biology

Molecular and Cellular Pathology

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