Research Topic

From Target to Market - Reflecting Global Issues in Drug Development Through the Summer School on Medicines (SSM) Initiative

About this Research Topic

Drug discovery and development is a long, interdisciplinary and expensive process. It usually starts from an idea that links a medical need to a particular target, and then follows a path (from idea to market, from bench to bedside) that includes target validation in the context of the clinical indication, discovery of hit compounds, optimization of hit into lead compounds, optimization of lead compounds into preclinical candidates (pharmacokinetics, toxicology), preclinical safety, clinical phases I, II and III, registration with regulatory entities, market approval, and pharmacovigilance (phase IV).

The first edition of the Summer School on Medicines (SSM) was held in 2009, with the proposal of covering all these steps with speakers from academia and industry. Since then, the 9 following editions of the SSM initiative have trained almost 300 people from more than 15 countries.

In this Research Topic, we welcome Original Research, Reviews, or Perspective articles from scientists from different disciplines and therapeutic areas, from any of the steps of the drug discovery and development process. Works can be experimental or computational, or on aspects related to the processes, including business development, market access, knowledge transfer, etc.

Therefore, the main goals of this Research Topic are to gather new discovery strategies and technological approaches that contribute to the optimization of the drug discovery and development processes; to deliver original interdisciplinary research papers or reviews; to present state-of-the-art drug discovery journey from idea to market.


Keywords: Drug-discovery, hit discovery/optimization, preclinical/clinical trials, pharmacokinetics, regulatory


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Drug discovery and development is a long, interdisciplinary and expensive process. It usually starts from an idea that links a medical need to a particular target, and then follows a path (from idea to market, from bench to bedside) that includes target validation in the context of the clinical indication, discovery of hit compounds, optimization of hit into lead compounds, optimization of lead compounds into preclinical candidates (pharmacokinetics, toxicology), preclinical safety, clinical phases I, II and III, registration with regulatory entities, market approval, and pharmacovigilance (phase IV).

The first edition of the Summer School on Medicines (SSM) was held in 2009, with the proposal of covering all these steps with speakers from academia and industry. Since then, the 9 following editions of the SSM initiative have trained almost 300 people from more than 15 countries.

In this Research Topic, we welcome Original Research, Reviews, or Perspective articles from scientists from different disciplines and therapeutic areas, from any of the steps of the drug discovery and development process. Works can be experimental or computational, or on aspects related to the processes, including business development, market access, knowledge transfer, etc.

Therefore, the main goals of this Research Topic are to gather new discovery strategies and technological approaches that contribute to the optimization of the drug discovery and development processes; to deliver original interdisciplinary research papers or reviews; to present state-of-the-art drug discovery journey from idea to market.


Keywords: Drug-discovery, hit discovery/optimization, preclinical/clinical trials, pharmacokinetics, regulatory


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

04 November 2018 Abstract
04 March 2019 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

04 November 2018 Abstract
04 March 2019 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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