Research Topic

Chromatin Stability and Dynamics: Targeting and Recruitment of Chromatin Modifiers

About this Research Topic

Chromatin, the complex structure that results from the interaction between DNA and nuclear proteins, organises the nuclear genome in the restricted space of the nucleus in which diverse processes occur in the absence of internal membranes. as occurs, for instance, within the cytoplasm thanks to organelle ...

Chromatin, the complex structure that results from the interaction between DNA and nuclear proteins, organises the nuclear genome in the restricted space of the nucleus in which diverse processes occur in the absence of internal membranes. as occurs, for instance, within the cytoplasm thanks to organelle membranes. Chromatin structure is highly dynamic allowing the unconstrained but controlled reprogramming of the nuclear processes, such as gene expression, in response to internal and external cues. This is particularly important in plants that, as sessile organisms, have to modify their development and growth depending on the combined action of their own internal signals and the environment.

Chromatin remodeling mechanisms responsible for modifying the structure of chromatin therefore add another layer in the regulation of gene expression decisively contributing to plant phenotypes. Despite the powerful plasticity of chromatin remodeling in controlling gene expression, the organisation of nuclear space is a key element in the maintenance of specific chromatin states during cell division which ensures determination and perpetuation of cell fate. In these two principally antagonistic functions, the recruitment of specific chromatin modifiers to precise target regions within the chromatin represents a decisive role for establishing new transcriptional states.

This Research Topic focuses on recent breakthroughs in our understanding of the complex balance between dynamics and stability of chromatin states. We therefore welcome contributions related to:

- Mitotic maintenance of chromatin states
- Preservation of the chromatin status through S-phase
- Resetting of chromatin states through chromatin re-modelling
- Chromatin rearrangements
- Recruitment of chromatin modifiers through transcription factors and other components of the transcription machinery
- Involvement of RNAs in the recruitment of chromatin modifiers
- Contribution of cis-elements and DNA conformation in the interaction of chromatin modifiers
- Role of chromatin modifications and structure in the binding with chromatin modifiers
- Interactions among different chromatin modifiers


Keywords: Chromatin, Chromatin modifiers, Cis-elements


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

25 October 2019 Manuscript
22 November 2019 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

25 October 2019 Manuscript
22 November 2019 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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