About this Research Topic
Current interest in sex and gender differences in pain, with respect to both biological and psychosocial mechanisms, such as emotions and coping, is escalating. It is known that there are biological, psychological, and social influences on pain. It is now time to take this knowledge of pain biology and psychology specific to sex and gender to focus on gender and sex-specific treatments. There has been a great deal of research on the biological and psycho-social aspects; however, sex and gender-specific treatment is a topic that has largely been neglected within this context. Therefore, there is a clear gap in translating what we know to foster research and move forward towards better treatments for pain. This field is slowly advancing and it is expected that more research results will be available in the near future to integrate bio-psycho-social elements of pain into treatment strategies and prevention with a focus on sex and gender differences. Individual differences exist, and sex and gender are among those elements that can have an influence on pain but also in response to prevention strategies and treatments. The absence of a sex and gender difference in pain is equally important for further therapeutic strategies. This Research Topic is intended to encourage research that takes sex and gender differences or lack of differences into consideration.
Pain and analgesic responses in children, adolescents, and adults are different. Therefore, it is also important to consider the age and how that can influence sex and gender-related differences over the life span in terms of prevention or therapy.
Manuscripts paving the way towards a better understanding of why females and males are different in pain processing and giving future directions towards sex and gender-specific treatments are welcome in this Research Topic.
Subtopics of interest include, but are not limited to:
• Pain biology (e.g., neuronal and non-neuronal, immune system, genetics, and epigenetics)
• Pain psychology (e.g., perception, cognitive, and coping strategies)
• Pain sociology (e.g., socio-cultural aspects)
• Pain prevention and treatments
The overall objective of this Research Topic is to explore the need for sex and gender-specific treatments for pain, and how current knowledge can be implemented into practice. Submissions of the following article types are welcome: Brief Research Report, Case Report, Clinical Trial, Community Case Study, Conceptual Analysis, Data Report, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Registered Report, Review, Systematic Review.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.