Research Topic

Hydronephrosis Associated with Ureteropelvic Junction Anomalies: An Ongoing Challenge

About this Research Topic

Although many diagnostics such as ultrasound, renal scan and Magnetic Resonance Urography (MRU) are available, there are still no specific findings suggesting significant renal damage or need of surgery for Ureteropelvic Junction type hydronephrosis (UPJHN) or obstruction. Many grading systems have been ...

Although many diagnostics such as ultrasound, renal scan and Magnetic Resonance Urography (MRU) are available, there are still no specific findings suggesting significant renal damage or need of surgery for Ureteropelvic Junction type hydronephrosis (UPJHN) or obstruction. Many grading systems have been developed to specify criteria or risk factors suggesting who can safely be followed nonoperatively and who will require surgery. The surgical treatment of UPJ type hydronephrosis is mostly carried out by mini incisional (minimal invasive) open surgery, laparoscopy or robotic pyeloplasty – there are however not enough data yet to determine the best alternative.

In this Research Topic, we would like to focus on the etiology of UPJ type hydronephrosis from its embryonal development, its pathophysiology and mechanisms, as well as the particular diagnosis and treatment options and follow-ups. In particular, we welcome articles that outline the most recent findings on diagnostic criteria to promptly determine the severity of hydronephrosis and thus predict which patients may develop significant obstruction and renal damage and who need surgery compared with who can safely be followed up nonoperatively. In addition, we wish to determine criteria which help clinicians decide which surgical alternative is superior according to findings and ages of children.

We encourage authors to submit articles focusing on following areas:
• Embryology and morphological (mal) development of UPJ
• Etiology, pathophysiology and mechanism of UPJ type hydronephrosis
• Natural history of fetal hydronephrosis
• Hydronephrosis and renal dysplasia
• Prenatal diagnosis and findings of UPJHN
• Fetal Urine and blood sampling, analyses and markers in fetal renal dysfunction
• Genetic screening and prenatal treatment of fetal hydronephrosis
• Dynamics and urodynamics of renal pelvis in UPJHN
• Differential diagnosis, parameters and interpretation of UPJHN
• Role of VCUG in antenatally diagnosed hydronephrosis
• Experimental and clinical results of UPJHN
• Urinary ultrasound and other imaging for UPJHN
• Nuclear medicine experience: Which renal scintigraphy? When? Why?
• Grading of hydronephrosis: problems and controversies
• Correct method (Single-Kidney GFR measurement etc.) to follow up
• When surgery when not to surgery in primary UPJHN (Indications for nonoperative follow up and surgery)
• Conservative follow up in natural history of UPJHN
• Risks and complications of nonoperative follow up
• The role of primary cystoscopic stenting of UPJHN
• Mini incisional pyeloplasty
• Transperitoneal Laparoscopic pyeloplasty
• Retroperitoneal Laparoscopic pyeloplasty
• Robotic pyeloplasty
• Stented versus nonstented pyeloplastyHow to drain renal and perirenal area
• Research on the ideal duration before/in between follow-ups for conservative vs surgical patients
• Long-term results of pyeloplasty
• Evaluation and planning research in UPJHN


Keywords: Ureteropelvic junction, hydronephrosis, severity, treatment


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

28 February 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

28 February 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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