About this Research Topic
Actinobacteria is a large group of prokaryotic microorganisms, originally recognized as a major population of terrestrial microbes, the prolific producers of useful natural compounds. The predominant genus Streptomyces is of great importance in human health, agriculture, bioremediation and environmental management. Antibiotics produced by Streptomyces spp. (such as actinomycin, chloramphenicol, erythromycin, streptomycin or tetracycline) have a major importance for public health worldwide.
With advances in DNA sequencing technologies and various -omics (metagenomics, metaproteomics etc.) studies, researchers are able to get better understanding of actinobacterial speciation, evolution, metabolic mechanisms, and also their interaction with the biotic and abiotic factors. The investigation of actinobacterial diversity, including the Streptomyces and the rare Actinobacteria, is of more and more great significance.
Different ecosystem accommodates various Actinobacteria and endows these microorganisms distinct characteristics, including their genetics properties, and a wide spectrum of physiological and metabolic activities. These characteristics distinguish this group of microorganisms from others, and in turn help them survive in diverse environments. Therefore, it is of immense interest to reveal the diversity of the Actinobacteria and their survival mechanisms, and subsequently expound the application of their secondary metabolic products.
The aim of this Research Topic is to compile original research articles, reviews or opinions focusing on the following two aspects:
• Distribution, genetic diversity and survival mechanisms of Actinobacteria in various environments.
• Diversity of secondary metabolites produced by these Actinobacteria.
Results from culture-dependent methods, omics studies and the technologies of synthetic biology are welcome.
Keywords: Actinobacteria, diversity, distribution, survival mechanism, secondary metabolites