About this Research Topic
Bioresponsive nanomaterials interfacing specific biologic environments of diseases for multimodality imaging or therapy have attracted much attention recently. They promise great improvement to existing imaging and therapeutic methods in clinics. Both the efficiency and safety of theranostics have been enhanced due to their bioresponsive characteristics. The past few decades have witnessed great efforts in synthesizing bioresponsive nanomaterials for the single or multimodal imaging of diseases (fluorescence imaging, magnetic resonance imaging (MRI), positron emission tomography (PET) imaging, photoacoustic imaging , etc.) and therapy such as chemotherapy, radiotherapy, photothermal therapy (PTT), photodynamic therapy (PDT), chemodynamic therapy (CDT), starving therapy, etc. This imaging technology could be used for imaging-guided therapy or to monitor therapeutic outcomes in real time.
Recent progress in the synthesis and functionalization of different kinds of organic or inorganic bioresponsive nanomaterials has greatly advanced the area, but obtaining effective nanoplatforms with controllable and bioresponsive properties still remain a challenge. Multi-bioresponsive or sequential bioresponsive nanotheranostics also need to be developed. Synergistic effects in both multimodality imaging or/and multi-therapy can be adjusted to maximize the diagnostic and therapeutic efficacies of different diseases in biomedical settings. Therefore, by integrating complex biologic environments and the inherent bioresponsive nature of nanoplatforms, we anticipate that bioresponsive nanomaterials will open up new horizons for diagnosis, treatment, and theranostics. This Research Topic aims to cover promising and novel research trends in bioresponsive nanomaterials for multimodal imaging and therapy of different diseases, providing a forum for the exchange of both clinical and scientific information in development of bioresponsive nanosystems.
We welcome both Original Research and Review articles. Potential subjects include but are not limited to the following:
• Design and preparation of bioresponsive nanoplatorms
• Bioresponsive nanomaterials for cancer multimodal imaging or imaging-guided therapy
• New bioresponsive nanomedicines to overcome complex biologic environment
• Investigation of the interactions between naomaterials and biologic barriers
• Biosafety analysis of bioresponsive nanomaterials
Keywords: Nanomedicine, Multimodality imaging, Theranostics, Bio-responsive, Therapy
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