About this Research Topic
Tumor ablation is defined as the direct application of chemical or thermal therapy to a tumor to achieve eradication or substantial tumor destruction. Currently, minimally invasive ablation techniques have become available for local destruction of focal tumors in multiple organ sites including liver, kidney, adrenal, lung, thyroid, parathyroid, breast, bone and more. Among ablation techniques, thermal ablation is a relatively low-risk procedure based on the biological response to tissue hyper- or hypothermia. Radiofrequency ablation is the most widely used ablation treatment for the majority of tumors. Because of several advantages including higher thermal efficiency, higher capability of coagulating blood vessels, faster ablation time, and simultaneous application of multiple antennae, microwave ablation could be a promising minimally invasive ablation technique for the treatment of solid tumors. Therefore microwave ablation has achieved rapid development in recent decades in China, the USA, and several European countries. Many successful tests have been done and a wide use has been achieved in multiple types of tumors, especially in liver and kidney cancer. With the rapidly developing technique of ablation, some experienced researchers have begun to pursue precision ablation in recent years. Image fusion technique and 3D visualization ablation planning system contribute to guiding ablation and assessing the ablation margin in a tumor. Nano-particles with drug-carrying properties help to enhance the ablation effect and thermal ablation can be applied by combination with target drug delivery and immunotherapy. With advanced techniques, tumor ablation will be established on a platform of precision, scientificity, safety, and efficiency.
The aim of the Research Topic is to provide an overview of recent advances in the field of image-guided tumor ablation and immune microenvironment changes induced by this technique. Heterogeneous topics in all areas of cancer ablation, spanning from in vitro experimental work to clinical studies, will be covered. We welcome original research, case report, mini-review and review articles that address, but are not limited to the following topics:
1) Outcome analysis of radiofrequency ablation in liver metastasis: perivascular location vs non-perivascular location.
2) The role of contrast-enhanced ultrasound in recurrent HCC after RFA.
3) Basic studies in tumor micro-environment after liver tumor ablation.
4) Learning curve of thermal ablation for liver cancers.
5) Microwave ablation in breast cancer.
6) History of ablation in Asia.
7) History of tumor ablation and future perspective.
Keywords: image, microwave, radiofrequency, ablation, tumors
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