About this Research Topic
Aging is the most important risk factor for the largest part of chronic disease morbidity and mortality. In a time where the world’s population consists of over 617 million aged 65 and over, geroscience is emerging as an imperative research focus in many disease pathologies. Aging equally represents the main risk factor for chronic lung diseases including lung cancer, chronic obstructive pulmonary disease, and pulmonary fibrosis. Furthermore, aging is linked with an increased susceptibility to acute respiratory disease, especially in the critically ill elderly patient. Although respiratory disease affects both young and old, the course might be different not only due to aging processes itself but also due to concomitant comorbidities.
The scope of this Research Topic is to raise awareness of respiratory diseases in the elderly. We are interested in manuscripts that help define and characterize acute and chronic respiratory diseases, such as pneumonia, critical illness related to acute lung injury, chronic obstructive pulmonary disease, asthma, interstitial lung diseases, pulmonary vascular disease in the elderly and their treatment implications. We are further interested in molecular mechanisms and signalling pathways contributing to increased susceptibility for disease and comorbidities in the elderly.
We are looking for clinical and translational research to help identify novel biomarkers and targets that either predict or contribute to progression of acute and chronic age-related respiratory disease. The topic also aims to include studies that focus on potential future treatment strategies to treat the different respiratory disease entities, targeted for the elderly population.
For these purposes, we will include original, review and perspective articles, commentaries and unique case reports with the hope that this topic will provide us with an update in the characterization and potential treatment of respiratory diseases in the elderly.
Keywords: Lung Disease, Aging, Inflammation, Senescence, Comorbidity
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.