Research Topic

Host-pathogen Interaction in Central Nervous System Infection

About this Research Topic

Meningitis is an inflammation of the meninges that cover and protect the brain and the spinal cord. This inflammation occurs upon an infection of the Central Nervous System, and etiological causes of infection can be bacteria, viruses, fungi, and also in rare cases parasites.

Pathogens in the brain encounter different types of cells, such as:

a) microglia, the resident macrophages of the brain,
b) neurons, the main cellular component responsible for electrical and chemical signaling, which is critical for all functions of the brain,
c) astrocytes, cells in close contact with the blood-brain barrier that participate in immune responses,
d) and other infiltrating immune cells.

The scope of this Research Topic is to shed light on all various types of interaction that the different etiological agents of meningitis (bacteria, viruses, fungi, parasites) take with the different cell types of the brain during the pathogenesis process.


Keywords: Meningitis, Central Nervous System, Microglia, Neurons, Astrocytes


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Meningitis is an inflammation of the meninges that cover and protect the brain and the spinal cord. This inflammation occurs upon an infection of the Central Nervous System, and etiological causes of infection can be bacteria, viruses, fungi, and also in rare cases parasites.

Pathogens in the brain encounter different types of cells, such as:

a) microglia, the resident macrophages of the brain,
b) neurons, the main cellular component responsible for electrical and chemical signaling, which is critical for all functions of the brain,
c) astrocytes, cells in close contact with the blood-brain barrier that participate in immune responses,
d) and other infiltrating immune cells.

The scope of this Research Topic is to shed light on all various types of interaction that the different etiological agents of meningitis (bacteria, viruses, fungi, parasites) take with the different cell types of the brain during the pathogenesis process.


Keywords: Meningitis, Central Nervous System, Microglia, Neurons, Astrocytes


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

02 August 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

02 August 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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