About this Research Topic
Meningitis is an inflammation of the meninges that cover and protect the brain and the spinal cord. This inflammation occurs upon an infection of the Central Nervous System, and etiological causes of infection can be bacteria, viruses, fungi, and also in rare cases parasites.
Pathogens in the brain encounter different types of cells, such as:
a) microglia, the resident macrophages of the brain,
b) neurons, the main cellular component responsible for electrical and chemical signaling, which is critical for all functions of the brain,
c) astrocytes, cells in close contact with the blood-brain barrier that participate in immune responses,
d) and other infiltrating immune cells.
The scope of this Research Topic is to shed light on all various types of interaction that the different etiological agents of meningitis (bacteria, viruses, fungi, parasites) take with the different cell types of the brain during the pathogenesis process.
Keywords: Meningitis, Central Nervous System, Microglia, Neurons, Astrocytes
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