About this Research Topic
In the past decade, many different kinds of ABPs have been developed for the therapy of cancer, cardiovascular, and neurology diseases. However, more investigations in the field are still in demand, such as continuous development of novel ABPs that can identify more critical enzymes in the organism, or improvement of the pharmaceutical kinetics and specificity of ABPs to get more rapid and precise recognition by the target enzymes. Furthermore, a combination of ABP-based assays and imaging of relevant biological processes is necessary to understand the function of the enzyme in cancer or other diseases. Furthermore, ABPs for multi-modal imaging and theranostic application have extended their application in biology and more studies are needed to increase the effectiveness of ABPs in these applications.
This Research Topic focuses on the development and application of ABPs. We welcome manuscripts that deal with the synthesis of novel ABPs and their use in (multi-modal) imaging, theranostics, and enzyme inhibitor discovery.
Keywords: activity-based probes, enzyme monitoring, enzyme inhibitor, multimodal imaging, theranostics
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.