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Scope
The Chemical Biology section publishes significant fundamental and applied advances across all aspects of chemical biology, a rapidly growing field at the interface of chemistry and biology. This interdisciplinary forum highlights new chemical tools and techniques to visualize, understand and manipulate biological systems and processes at the molecular level.
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Scope
The Chemical Biology section publishes significant fundamental and applied advances across all aspects of chemical biology, a rapidly growing field at the interface of chemistry and biology. This interdisciplinary forum highlights new chemical tools and techniques to visualize, understand and manipulate biological systems and processes at the molecular level. Topics include, but are not limited to:
· Mechanistic studies on carbohydrates, lipids, peptides, proteins and nucleic acids
· Protein and enzyme design and engineering
· Enzyme mechanism and biosynthesis of natural products
· Biological systems engineered to perform novel chemical transformations
· Intra- and intercellular communication mediated by small molecules
· Design and use of novel molecular systems as tools to study synthetic and systems biology
· Special chemical techniques (e.g. click chemistry and molecular imaging) to study biomolecules in living cells and organisms
· Generation, distribution and function of small molecule-protein conjugates
· Novel molecular probes to identify and characterize potential therapeutic targets
· Large-scale studies enabled by the use of chemistry-based technology: proteomics, lipidomics, metabolomics and glycomics
This section has a particular focus on applications of chemical biology approaches to fields such as medicinal chemistry, biochemistry, chemical genetics, structural biology, cell biology, glycobiology, systems biology, nanotechnology, pharmacology, immunology, microbiology, neuroscience and oncology. All studies must provide significant conceptual or methodological advances, and descriptive or phenomenological studies do not fall within the scope of the section.
Indexed in: PubMed Central, Scopus, Web of Science, Google Scholar, DOAJ, CrossRef, Chemical Abstracts Service (CAS), CLOCKSS
PMCID: all published articles receive a PMCID
Chemical Biology welcomes submissions of the following article types: Book Review, Brief Research Report, Correction, Data Report, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review, Specialty Grand Challenge and Technology and Code.
All manuscripts must be submitted directly to the section Chemical Biology, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
Articles published in the section Chemical Biology will benefit from the Frontiers impact and tiering system after online publication. Authors of published original research with the highest impact, as judged democratically by the readers, will be invited by the Chief Editor to write a Frontiers Focused Review - a tier-climbing article. This is referred to as "democratic tiering". The author selection is based on article impact analytics of original research published in all Frontiers specialty journals and sections. Focused Reviews are centered on the original discovery, place it into a broader context, and aim to address the wider community across all of Chemistry.
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