About this Research Topic
The development of nanotechnology has experienced exponential growth in the past decade, still with an increasing promise to substantially benefit human health. Integrating research on nanotechnology and medical sciences, the burgeoning field of nanomedicines has invigorated a flurry of research interests and activities on diverse biomedical applications of nanomaterials, whether made from a natural or synthetic origin. With particular applications in cancer diagnosis and therapy, including hematological malignancy and solid tumors, nanotechnology-promoted reformations of traditional biotechnology, such as nanomaterial-modified drug delivery systems, bioimaging and therapeutics, significantly inspired and endorsed a rapid development in translational cancer medicine, attracting massive interest from medical researchers and pharmaceutical industries.
Amidst advances pushing cancer nanomedicines closer to clinical settings, nanotechnology-enhanced bioimaging showed unmatched sensitivity and resolution, visualizing the tumorigenesis/progression, or surgical/therapeutic process. This Research Topic aims to explore the latest developments of nanotechnology-enhanced bioimaging in cancer detection and treatment, within a special orientation for their clinical translation. Imaging modality spans from optically active bioluminescence and fluorescence, to radiologically traceable positron emission tomography (PET) and computed tomography (CT), with state-of-the-art techniques based on one specific imaging modality, such as near-infrared fluorescence imaging, or multimodality imaging, such as a combination of PET/CT, etc. Also, we are keen to investigate tumor samples that represent certain pathophysiological status in cancers, recently analyzed by nanotechnology-pertaining spectroscopic (e.g., surface-enhanced Raman spectroscopy) or microscopical (e.g., atomic force microscopy) techniques.
By this collection of studies, peer researchers can share a forum to present articles of Original Research or Review covering the following areas (recommended but are not limited to):
- Nanotechnology-enhanced bioluminescence imaging in monitoring cancer growth and/or metastasis.
- Advanced fluorescence techniques in cancer imaging, e.g., through near-infrared transparency windows or fluorescence emission beyond 1000 nm.
- Applications of nanoscale materials in radiologically active imaging approaches, such as PET/CT, etc., in early cancer diagnosis.
- Nanotechnology in improving spatial resolution of nuclear medicine, including magnetic resonance imaging.
- Nanoprobe-aided and imaging-guided detection, surgery, or/and treatment of cancers.
- Nanomaterial-pertaining novel bioimaging in cancer detection, like acoustic imaging.
- Nanotechnology improved pathophysiological analyses on cancer samples.
- Multimodality imaging in nanoparticle-improved cancer detection, delivery, and therapeutics.
Keywords: nanotechnology, nanomaterial, imaging, cancer, translational medicine, diagnosis, treatment
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