Research Topic

Regulation Mechanism of Adipose-Derived Stem Cells in Differentiation and Translation

About this Research Topic

Adipose-derived stem cells (ASCs) are isolated from adipose tissue, a kind of stem cells with multi-lineage differentiation ability. They are distributed in the space around the vascular system of the adipose tissue. ASCs are from extensive sources and abundant reserves in the body. Therefore, it is suitable for conducting autologous transplantation and seed cells for the construction of tissue-engineered fat tissue, which gradually becomes a hot research area.

A better understanding of how the development of fat tissue is regulated and which control mechanisms are involved are of great interest to this Research Topic. Furthermore, we are also interested in unravelling the mechanisms behind ASCs differentiation. The aim of this article collection is to promote our understanding of the effects of changing physiological conditions on the fat tissue and to help develop methods for the treatment and prevention of obesity.

This Research Topic is intended to show readers the basic research on the regulatory mechanisms of adipose-derived stem cells and the related clinical translation progress. We welcome Original research, Review, and Mini-Review articles. Areas to be covered in this article collection may include, but are not limited to the following subtopics:

• The molecular biological regulatory mechanisms of ASCs in differentiation
• The immunoregulatory mechanisms of ASCs
• The perspectives for clinical translation of ASCs
• The role of fatty acid metabolism in maintenance and differentiation of stem cells


Keywords: adipose-derived stem cells, differentiation, Regulation mechanism, translation medicine, Regenerative medicine


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Adipose-derived stem cells (ASCs) are isolated from adipose tissue, a kind of stem cells with multi-lineage differentiation ability. They are distributed in the space around the vascular system of the adipose tissue. ASCs are from extensive sources and abundant reserves in the body. Therefore, it is suitable for conducting autologous transplantation and seed cells for the construction of tissue-engineered fat tissue, which gradually becomes a hot research area.

A better understanding of how the development of fat tissue is regulated and which control mechanisms are involved are of great interest to this Research Topic. Furthermore, we are also interested in unravelling the mechanisms behind ASCs differentiation. The aim of this article collection is to promote our understanding of the effects of changing physiological conditions on the fat tissue and to help develop methods for the treatment and prevention of obesity.

This Research Topic is intended to show readers the basic research on the regulatory mechanisms of adipose-derived stem cells and the related clinical translation progress. We welcome Original research, Review, and Mini-Review articles. Areas to be covered in this article collection may include, but are not limited to the following subtopics:

• The molecular biological regulatory mechanisms of ASCs in differentiation
• The immunoregulatory mechanisms of ASCs
• The perspectives for clinical translation of ASCs
• The role of fatty acid metabolism in maintenance and differentiation of stem cells


Keywords: adipose-derived stem cells, differentiation, Regulation mechanism, translation medicine, Regenerative medicine


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

31 March 2021 Abstract
31 July 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

31 March 2021 Abstract
31 July 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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