About this Research Topic
Cardiomyopathies are a heterogeneous group of diseases of the myocardium with different etiologies. Infection, inflammation, and immune reactions are all involved in the physiopathology of cardiomyopathies, regardless of their trigger. Parasitic infections, which are often associated with cardiac manifestations, account for a great deal of morbidity and mortality in extensive areas of the world, especially in developing countries. Some of these infections may affect the anatomic structures of the heart, such as the myocardium and pericardium, as well as the pulmonary vasculature, producing a wide variety of cardiac manifestations. As an example, Chagas disease, caused by the protozoan Trypanosoma cruzi, is a major cause of cardiomyopathies worldwide. In addition to Chagas disease, other parasitic and infectious diseases may also lead to cardiomyopathies. Although previously observed only in endemic areas, cardiomyopathies related to parasitic infections can currently be diagnosed anywhere around the globe due to growing migration. Thus, all clinicians must be aware of the potential cardiac manifestations induced by these infectious diseases, with the goal of bettering prevention, treatment, and clinical management.
Appropriate management of patients with parasitic and infectious cardiomyopathies requires specialized clinical expertise to recognize features of these diseases for correct diagnosis and treatment.
The main goal of this research topic is to improve current clinical knowledge of these cardiomyopathies, while also providing information regarding their epidemiology, prevention, treatment, and management. In addition, we intend to present recent advances in clinical and molecular features, including biomarkers of disease progression and/or cure, to instruct patient care. We believe that this topic will guide general practitioners and cardiologists in the identification and treatment of parasitic and infectious cardiomyopathies.
We will bring together a strong group of scientific contributors to discuss clinical and molecular aspects of cardiomyopathies caused by parasitic and infectious diseases. We are looking for submissions in the following areas, but we are not restricted to them and will be welcoming all high-quality contributions.
1: Chagas disease
3: Tropical endomyocardial fibrosis
We welcome all types of manuscripts, including original basic science reports, review articles, methodology papers, translational research, and clinical studies.
Keywords: Cardiomyopathies, parasitic cardiomyopathies, infectious cardiomyopathies, Chagas disease, schistosomiasis, tropical endomyocardial fibrosis, myocarditis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.