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Frontiers in Cardiovascular Medicine is a global, peer-reviewed Open Access medical journal providing unrestricted, online access to publications on diagnostic and therapeutic advances in cardiology and cardiovascular disease. Frontiers in Cardiovascular Medicine publishes peer-reviewed scientific investigations of the highest quality that are of relevance for the diagnosis, treatment, or pathogenesis of cardiovascular disease and related disorders with the goal to understand disease processes and to improve medical practice and patient care.
From the starting point of an individual’s genome sequence to the onset of cardiovascular disease, there is a complex interplay of genetic and environmental influences on cardiovascular disease. For example, mental stress represents an environmental stimulus that might differentially affect individuals’ risk across a broad spectrum of cardiovascular disorders from arrhythmias to high blood pressure, cardiovascular metabolism and heart failure.
A systems medicine approach would integrate such relevant physiologic and behavioral factors that could potentially influence the genesis of cardiovascular disorders, as well as individual response to treatment. Advances in digital technology will make it possible to monitor each individual’s cardiovascular health in the context of their unique socio-demographic, economic and cultural influences. The goal of personalized and patient-centered approach to cardiovascular medicine should fully integrate the context of care and individual characteristics, such as gender, ethnicity, culture, health literacy, education level, income, and geography.
The mission of General Cardiovascular Medicine is to advance our understanding of personalized approaches to cardiovascular diagnosis and treatment, beginning with the patient physician communication, to bedside clinical assessment, advanced diagnostic and imaging technologies. General Cardiovascular Medicine welcomes submissions on models of integrated patient-centered cardiovascular care. The Editors encourage a broad range of research methodologies such as clinical trials, population studies, database reviews, comparative effectiveness and pragmatic trials, as well as preclinical models of care. The Editors are also interested in models of care and decision support that generate evidence-based approaches to cardiovascular care across diverse populations.
The Editors of Frontiers in Cardiovascular Medicine encourage submission of Original Research Articles (clinical or preclinical), Reviews, Mini Reviews and Case Reports. Original research articles include manuscripts reporting results from clinical investigations, including Phase I-III trials and population studies. Reports from experimental studies from related areas such as physiology, pathophysiology, cellular and molecular biology, genetics, or pharmacology may be considered as as long as they relate to new understandings of pathogenic mechanisms or novel therapeutic approaches relevant to human disease. Articles related to medical education or the future development of medicine may also be considered.
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PMCID: all published articles receive a PMCID
General Cardiovascular Medicine welcomes submissions of the following article types: Case Report, Clinical Trial, Correction, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Policy and Practice Reviews, Review, Study Protocol and Systematic Review.
All manuscripts must be submitted directly to the section General Cardiovascular Medicine, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
Articles published in the section General Cardiovascular Medicine will benefit from the Frontiers impact and tiering system after online publication. Authors of published original research with the highest impact, as judged democratically by the readers, will be invited by the Chief Editor to write a Frontiers Focused Review - a tier-climbing article. This is referred to as "democratic tiering". The author selection is based on article impact analytics of original research published in all Frontiers specialty journals and sections. Focused Reviews are centered on the original discovery, place it into a broader context, and aim to address the wider community across all of Cardiovascular Medicine.
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