Research Topic

Immunometabolism, atherosclerosis, and metabolic diseases

About this Research Topic

Immune cells, including macrophages, play a central role in the pathogenesis of atherosclerosis and metabolic diseases. In response to inflammatory stimuli, immune cells reconfigure cellular metabolism and bioenergetics. Alterations in the metabolic profile of immune cells shape their activation state and ...

Immune cells, including macrophages, play a central role in the pathogenesis of atherosclerosis and metabolic diseases. In response to inflammatory stimuli, immune cells reconfigure cellular metabolism and bioenergetics. Alterations in the metabolic profile of immune cells shape their activation state and function. Understanding the metabolic reprogramming of immune cells could aid in drug discovery and development to treat or prevent inflammatory, metabolic diseases.
To date, how immune cells rewire intracellular metabolism in response to inflammatory and metabolic stress is not fully understood. Further, it is less clear regarding the reciprocal regulation between immune cells and metabolic tissues in the context of metabolic diseases. We are interested in studies to address these key research questions.
The scope of the research topic is immunometabolism, including intercellular immunometabolism (crosstalk between immune cells and metabolic tissues, including liver and adipose tissue) and intracellular immunometabolism (regulation of immune cell function via metabolic reprogramming, focusing on lipid metabolism).


Keywords: Lipid metabolism, glucose metabolism, macrophages, inflammation, inflammasome, autophagy, oxidative stress, redox, immunometabolism, PUFAs, saturated fatty acids, atherosclerosis, metabolic diseases


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent Articles

Loading..

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

31 May 2021 Abstract
30 September 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

Loading..

Topic Editors

Loading..

Submission Deadlines

31 May 2021 Abstract
30 September 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..