About this Research Topic
In mammalian development, the two windows for epigenetic reprogramming are germ cell formation and early embryo development. The reestablishment of epigenetic modifications is essential for oocyte maturation and embryonic development. Recently, it is indicated that epigenetic modifications play a key role in the inheritance of noncommunicable diseases. And epigenetic reprogramming is prone disrupted by environmental factors. Therefore, to understand how intra- and extra-environment affects epigenetic reprogramming in gametes and embryos is extremely important to develop strategies to prevent the inheritance of noncommunicable diseases.
This Research Topic aims to provide an updated knowledge on understanding the molecular mechanisms involved in game maturation and environmental factors affecting embryonic development and adult health. We welcome the submissions of Original Research, Methods, Review and Mini-Review articles that cover, but are not limited to, the following topics:
• Metabolic disorders and gametogenesis
• Effects of intra- and extra-environmental factors on epigenetics
• Intra- and extra-environment and embryonic quality
• Inheritance of noncommunicable diseases
• Strategies to prevent effects of environmental factors on reproduction
• Germ cell development and maturation
Keywords: germ cell, mitochondria, reproduction, environment, epigenetics, embryo
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.