Thyroid cancer continues to be the leading head and neck cancer, tripling its prevalence within the last three decades. This continuous increase in new thyroid cancer cases, together with its known excellent prognosis for well differentiated thyroid cancer, have led to a growing emphasis on quality of life of thyroid cancer patients, rather than a sole focus on complete tumor excision and adjuvant treatments. Important efforts were made to reduce surgical burden of low-risk tumors, as well diagnostic surgeries. Other aspects relate to the use of technologies to minimize possible complications and adverse outcome of thyroid surgery – use of intra-operative nerve monitoring to reduce recurrent laryngeal nerve injury, remote surgical approaches which avoid apparent neck scars and more.
Despite suggested changes in the management of low-risk thyroid cancer, conservative management of well differentiated cancer, which may include limited surgery, active surveillance or remote approach surgery, has not been adopted worldwide and has yet to be regarded as consensus. The decrease of radioactive iodine treatment for low-risk patients has raised concerns regarding possible implication on recurrence rates by some. Similarly, use of intraoperative nerve monitoring has become common practice and even mandatory in some countries, yet opponents question its cost-effectiveness and proven benefits.
This Research Topic aims to increase our current evidence data on current management changes on quality of life in on hand, and oncologic safety on the other. We welcome submissions of Original Research, Reviews, and Mini-Reviews focusing on well differentiated thyroid cancer, covering but not limited to the below aspects:
• Active surveillance for low-risk patients – patients’ selection, impact on quality of life, adherence to treatment and role of imaging
• New surgical developments which may lead to decreased complications rate
• Impact of radioactive iodine on quality of life of thyroid cancer patients
• Patients preferences and perspective for different treatments – conservative, limited surgery, remote access surgery or traditional surgery
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.
Thyroid cancer continues to be the leading head and neck cancer, tripling its prevalence within the last three decades. This continuous increase in new thyroid cancer cases, together with its known excellent prognosis for well differentiated thyroid cancer, have led to a growing emphasis on quality of life of thyroid cancer patients, rather than a sole focus on complete tumor excision and adjuvant treatments. Important efforts were made to reduce surgical burden of low-risk tumors, as well diagnostic surgeries. Other aspects relate to the use of technologies to minimize possible complications and adverse outcome of thyroid surgery – use of intra-operative nerve monitoring to reduce recurrent laryngeal nerve injury, remote surgical approaches which avoid apparent neck scars and more.
Despite suggested changes in the management of low-risk thyroid cancer, conservative management of well differentiated cancer, which may include limited surgery, active surveillance or remote approach surgery, has not been adopted worldwide and has yet to be regarded as consensus. The decrease of radioactive iodine treatment for low-risk patients has raised concerns regarding possible implication on recurrence rates by some. Similarly, use of intraoperative nerve monitoring has become common practice and even mandatory in some countries, yet opponents question its cost-effectiveness and proven benefits.
This Research Topic aims to increase our current evidence data on current management changes on quality of life in on hand, and oncologic safety on the other. We welcome submissions of Original Research, Reviews, and Mini-Reviews focusing on well differentiated thyroid cancer, covering but not limited to the below aspects:
• Active surveillance for low-risk patients – patients’ selection, impact on quality of life, adherence to treatment and role of imaging
• New surgical developments which may lead to decreased complications rate
• Impact of radioactive iodine on quality of life of thyroid cancer patients
• Patients preferences and perspective for different treatments – conservative, limited surgery, remote access surgery or traditional surgery
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review
Please note: manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by validation (independent cohort or biological validation in vitro or in vivo) are out of scope for this section and will not be accepted as part of this Research Topic.