Biological Matrices for Tissue Engineering Applications

Matrices derived from biological materials hold great promise for tissue engineering applications. Used as scaffolds or carrier materials, they offer several advantages compared to synthetic materials in terms of mimicking a physiological microenvironment that can be remodelled by the present cells, But also bioactivity, biodegradability and biocompatibility when applied in vivo.


This Research Topic issue aims at giving a comprehensive overview of biological matrices currently used for tissue engineering and their potential fields of application in vivo. This should include the most important and frequently utilized matrices such as collagen-, cellulose- or fibrin matrices, decellularized tissues or organs or spider silk. However, more novel or alternative approaches are also highly welcome to be included.


Authors are encouraged to submit review articles describing the role of biological scaffolds in orthopedic, skin and internal organ tissue engineering and drug delivery. Review articles focusing on the challenges of in vivo applications of natural-derived matrices are also highly welcome.
Furthermore, authors are strongly encouraged to submit original articles presenting interesting new data on topics within the scope of this Research Topic .