About this Research Topic
Toward industrialization of microalgal technology and engineering, developing next-generation microalgal chassis cells with designable and editable genomes, predictable and controlled physiological, and metabolic activities, and reliable cellular robustness in flexible environments would be significant. Achieving this goal will undoubtedly require a deeper understanding of genetic, physiological, and metabolic activities, more effective enabling approaches for synthetic biology, and more comprehensive genome modifications. Therefore, this topic emphasizes the progress and perspectives for engineering novel microalgal chassis cells with synthetic biology tools and other classical approaches.
Types of manuscripts to be featured mainly include Original Research, Brief Research Reports, and Reviews relevant to the theme of design, construction, and application of microalgal chassis cells. Please note that submissions must be hypothesis drivers. Topics covered may include, but are not limited to:
• Development and optimization of microalgal synthetic biology toolboxes for genome engineering and metabolic engineering
• Reconstruction and application of microalgal genome-scale metabolism models or networks
• Genome reduction or synthesis of microalgae both on in silico and in vivo scales
• Characterization, reconstruction, and modulization of physiological and metabolic functions in microalgae
• Evolution or redesign of microalgal chassis cells for improved photosynthesis efficiency and performances
• Development of microalgal cell factories for photosynthetic production of bioenergy, biochemicals, and other high-value-added products
• Optimization of microalgal industrial properties including (but not limited to) environmental stress tolerances and cell harvesting properties
Keywords: Microalgae, Cyanobacteria, Chassis cells, Synthetic biology, Genome engineering
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.