The role of nutritional status in the risk and course of infection is actively being investigated. Being involved in the normal function and modulation of all the biological processes, including the maintenance of healthy mucosal barriers and immune responses, macro - and micro - nutrients have a pleiotropic effect on the host health.
During the last decade, it has been demonstrated that nutrients, or their lack of, influence the susceptibility to infection and how the metabolic changes that occur during host-pathogen interaction impact on pathogen proliferation and pathogenicity.
Although malnutrition, obesity and the so called sarcopenic obesity are considered major determinants of increased susceptibility to infection, the metabolic mechanisms involved in this phenomenon are not yet fully understood. In addition, a multimodal approach to minimize the severity and incidence of infections and the following rehabilitation (including pharmaconutrients, physiotherapy and drugs) in malnourished/obese hosts is not fully optimized .
The aim of this Research Topic is to highlight advanced approaches for improving the nutritional and immunological status of malnourished/obese hosts, that causes a reduced susceptibility to infection. As such, this Research Topic welcomes submissions related to the important aspects of nutrition, metabolism, and infection, including, but not limited to:
- The role of vitamins in host response to infection and the effects of vitamin supplementation for prevention and treatment of infections;
-The characterization of molecular mechanisms and protein targets underlying the interactions between Nutrition, Metabolism and Infection
-The general aspects of nutritional status and the association of malnutrition, obesity and sarcopenic obesity with infectious diseases (including sepsis and COVID-19);
-The risk-benefit ratio of the un/controlled dietary supplementation of micro - and macro - nutrients and physiotherapy programs in acute and post-acute infectious diseases;
-The role of gut microbiota in clinical nutrition and infections (including sepsis and COVID-19);
-The characterization of regulatory metabolic mechanisms and signaling pathways, as activation or deactivation of specific metabolic programs according to nutritional status
-Drug-nutritional interactions
-The role of proteins in the metabolism of vitamins
-The association of pharmaconutrients and rehabilitation to improve clinical outcome in infectious diseases (including sepsis and COVID-19);
-Enteral/Parenteral nutrition and infections -the impact of calorie -, protein -, and calorie -protein malnutrition, vitamins, and mineral deficiencies as well as obesity in the susceptibility to infections;
Authors are encouraged to submit original manuscripts that focus on the interplay between nutrients and food microorganisms with the host, which influences the resistance to infections. We welcome original research, brief research reports, mini-review, and review articles that address the present issue.
The role of nutritional status in the risk and course of infection is actively being investigated. Being involved in the normal function and modulation of all the biological processes, including the maintenance of healthy mucosal barriers and immune responses, macro - and micro - nutrients have a pleiotropic effect on the host health.
During the last decade, it has been demonstrated that nutrients, or their lack of, influence the susceptibility to infection and how the metabolic changes that occur during host-pathogen interaction impact on pathogen proliferation and pathogenicity.
Although malnutrition, obesity and the so called sarcopenic obesity are considered major determinants of increased susceptibility to infection, the metabolic mechanisms involved in this phenomenon are not yet fully understood. In addition, a multimodal approach to minimize the severity and incidence of infections and the following rehabilitation (including pharmaconutrients, physiotherapy and drugs) in malnourished/obese hosts is not fully optimized .
The aim of this Research Topic is to highlight advanced approaches for improving the nutritional and immunological status of malnourished/obese hosts, that causes a reduced susceptibility to infection. As such, this Research Topic welcomes submissions related to the important aspects of nutrition, metabolism, and infection, including, but not limited to:
- The role of vitamins in host response to infection and the effects of vitamin supplementation for prevention and treatment of infections;
-The characterization of molecular mechanisms and protein targets underlying the interactions between Nutrition, Metabolism and Infection
-The general aspects of nutritional status and the association of malnutrition, obesity and sarcopenic obesity with infectious diseases (including sepsis and COVID-19);
-The risk-benefit ratio of the un/controlled dietary supplementation of micro - and macro - nutrients and physiotherapy programs in acute and post-acute infectious diseases;
-The role of gut microbiota in clinical nutrition and infections (including sepsis and COVID-19);
-The characterization of regulatory metabolic mechanisms and signaling pathways, as activation or deactivation of specific metabolic programs according to nutritional status
-Drug-nutritional interactions
-The role of proteins in the metabolism of vitamins
-The association of pharmaconutrients and rehabilitation to improve clinical outcome in infectious diseases (including sepsis and COVID-19);
-Enteral/Parenteral nutrition and infections -the impact of calorie -, protein -, and calorie -protein malnutrition, vitamins, and mineral deficiencies as well as obesity in the susceptibility to infections;
Authors are encouraged to submit original manuscripts that focus on the interplay between nutrients and food microorganisms with the host, which influences the resistance to infections. We welcome original research, brief research reports, mini-review, and review articles that address the present issue.
