Over the past few decades, the toxic and health effects of various environmental pollutants (including heavy metal, pesticides, PCBs, PPCPs, PAHs and microplastics, etc.) on non-target organisms (for example, mice, bees, birds, silkworms, earthworms, fishes, etc.) have received more and more attention. In addition, studies on the compound toxic effects of multiple environmental pollutants on non-target organisms are also very important. As a new omics technology, metabolomics can clarify the metabolic homeostasis of the organism at the overall level by studying the changes in the relative contents of endogenous metabolites in the organism. Some studies have used metabolomics technology to study the toxic effects of environmental pollutants on non-target organisms. However, there are still gaps in knowledge to be filled.
This research topic aims to cover the latest advances and updates in the study of the toxicology and health effects of environmental pollutants based on metabolomics. Integration study of the toxic effects of environmental pollutants based on metabolomics and other omics (such as transcriptomics, proteomics, microbiome, etc.) are welcome. A variety of article types will be considered, including Original Research, Reviews, Hypotheses and Theories, Methods, Mini-reviews and Perspectives.
This Research Topic includes, but is not limited to, the following themes:
• Metabolomics method development and validation for toxicological and health effects of environmental pollutants;
• Using metabolomics to comprehensively assess the health effects of environmental pollution on organisms and discover corresponding biomarkers for risk assessment;
• Using targeted metabolomics techniques to study the effects of environmental pollutants on specific metabolic pathways (e.g. amino acids, bile acids and short-chain fatty acids, etc.) of organisms;
• Combined toxicity of multiple pollutants on organisms based on metabolomics;
• Multi-omics studies involve metabolomics for the study of toxicological and health effects of environmental pollutants;
• Reform and innovation in the teaching of environmental toxicology based on metabolomics.
Over the past few decades, the toxic and health effects of various environmental pollutants (including heavy metal, pesticides, PCBs, PPCPs, PAHs and microplastics, etc.) on non-target organisms (for example, mice, bees, birds, silkworms, earthworms, fishes, etc.) have received more and more attention. In addition, studies on the compound toxic effects of multiple environmental pollutants on non-target organisms are also very important. As a new omics technology, metabolomics can clarify the metabolic homeostasis of the organism at the overall level by studying the changes in the relative contents of endogenous metabolites in the organism. Some studies have used metabolomics technology to study the toxic effects of environmental pollutants on non-target organisms. However, there are still gaps in knowledge to be filled.
This research topic aims to cover the latest advances and updates in the study of the toxicology and health effects of environmental pollutants based on metabolomics. Integration study of the toxic effects of environmental pollutants based on metabolomics and other omics (such as transcriptomics, proteomics, microbiome, etc.) are welcome. A variety of article types will be considered, including Original Research, Reviews, Hypotheses and Theories, Methods, Mini-reviews and Perspectives.
This Research Topic includes, but is not limited to, the following themes:
• Metabolomics method development and validation for toxicological and health effects of environmental pollutants;
• Using metabolomics to comprehensively assess the health effects of environmental pollution on organisms and discover corresponding biomarkers for risk assessment;
• Using targeted metabolomics techniques to study the effects of environmental pollutants on specific metabolic pathways (e.g. amino acids, bile acids and short-chain fatty acids, etc.) of organisms;
• Combined toxicity of multiple pollutants on organisms based on metabolomics;
• Multi-omics studies involve metabolomics for the study of toxicological and health effects of environmental pollutants;
• Reform and innovation in the teaching of environmental toxicology based on metabolomics.