Like terrestrial counterparts, marine organisms are diverse in species and residential environments. These interesting animals (such as fishes, shrimps, crabs, molluscs, and marine mammals), plants and microorganisms (such as algae and bacteria) can produce numerous bioactive peptides to fulfil important physiological roles, or for predation and defence. Many popular peptides, including antimicrobial peptides (AMPs), antihypertensive peptides (AHTPs), and conopeptides (also termed as conotoxins), have been developed as valuable research tools and marine drugs to improve our knowledge and health. In recent decades, with the rapid development of various powerful omics technologies (such as genomics, transcriptomics, proteomics, metagenomics, and metabolomics), worldwide scientists have applied them to identify, characterize and validate target genes and their encoded proteins in a high-throughput way, with an important aim to dig out critical bioactive peptides directly or by digestion with enzymes to generate useful bioactive peptides from longer protein sequences.
Due to the high diversity of marine species and their bioactive peptide sequences, international research teams have been busy with the identification, characterization and validation of numerous peptide sequences and their encoding genes for various biomedical purposes. Many important advances are emerging rapidly with the assistance of such big data-based omics technologies. A good academic platform, such as a special issue or topic, is therefore required to collect, publish, spread, and share these valuable data and results with worldwide scientists and businessmen. In-depth analyses and applications of this genetic resource may be realized efficiently by different research groups, and thereby enable various bioactive peptides to become useful and even powerful pharmaceuticals.
The present research topic focuses on omics-based advances of bioactive peptides and their encoding genes from individual or multiple marine species. Integration of multi-omics, validation or mechanism proposal of peptides’ functions, and development of new analytical tools, are also encouraged. Original and novel Research Article, Review, or Data Report related to one or more of the following topics are welcomed.
• Genome, transcriptome, proteome, metagenome, or metabolome profiling
• Identification and characterization of bioactive peptide sequences and their encoding genes
• In vivo or in vitro experimental validation of bioactive peptides
• Modeling of protein-peptide interactions and signaling networks
• Development of new algorithms, software, or pipelines for in silico exploration of novel bioactive peptides
Like terrestrial counterparts, marine organisms are diverse in species and residential environments. These interesting animals (such as fishes, shrimps, crabs, molluscs, and marine mammals), plants and microorganisms (such as algae and bacteria) can produce numerous bioactive peptides to fulfil important physiological roles, or for predation and defence. Many popular peptides, including antimicrobial peptides (AMPs), antihypertensive peptides (AHTPs), and conopeptides (also termed as conotoxins), have been developed as valuable research tools and marine drugs to improve our knowledge and health. In recent decades, with the rapid development of various powerful omics technologies (such as genomics, transcriptomics, proteomics, metagenomics, and metabolomics), worldwide scientists have applied them to identify, characterize and validate target genes and their encoded proteins in a high-throughput way, with an important aim to dig out critical bioactive peptides directly or by digestion with enzymes to generate useful bioactive peptides from longer protein sequences.
Due to the high diversity of marine species and their bioactive peptide sequences, international research teams have been busy with the identification, characterization and validation of numerous peptide sequences and their encoding genes for various biomedical purposes. Many important advances are emerging rapidly with the assistance of such big data-based omics technologies. A good academic platform, such as a special issue or topic, is therefore required to collect, publish, spread, and share these valuable data and results with worldwide scientists and businessmen. In-depth analyses and applications of this genetic resource may be realized efficiently by different research groups, and thereby enable various bioactive peptides to become useful and even powerful pharmaceuticals.
The present research topic focuses on omics-based advances of bioactive peptides and their encoding genes from individual or multiple marine species. Integration of multi-omics, validation or mechanism proposal of peptides’ functions, and development of new analytical tools, are also encouraged. Original and novel Research Article, Review, or Data Report related to one or more of the following topics are welcomed.
• Genome, transcriptome, proteome, metagenome, or metabolome profiling
• Identification and characterization of bioactive peptide sequences and their encoding genes
• In vivo or in vitro experimental validation of bioactive peptides
• Modeling of protein-peptide interactions and signaling networks
• Development of new algorithms, software, or pipelines for in silico exploration of novel bioactive peptides
