About this Research Topic
Immunomodulatory effects of the altered profile of gut microbiota play an important role in diabetes mellitus and tumor immunity. In this Research Topic, we aim to explore intestinal microflora profiles and the specific processes by which bacterial components, metabolites, and other mediators of intestinal microflora interact with the host to affect the immunity of patients with diabetes mellitus or cancer. Host immune responses are an extremely complex process, and in-depth exploration of the gut microbiota-host-disease relationship will be helpful to identify potential therapeutic targets for diabetes mellitus and cancer.
We encourage the exploration of the etiology and factors influencing diabetes mellitus and tumor immunity from an intestinal microecological perspective with the aim of addressing these challenging questions. Both Original Research and Review articles are welcomed here, including, but not limited to, the following research contents:
1. Correlation analysis of gut microbiota composition with diabetes mellitus and tumor immunity;
2. Molecules of intestinal microflora affecting host immune responses;
3. Mechanisms of specific intestinal microflora affecting the development of diabetes mellitus and tumor immunity;
4. Molecular mechanisms of bacterial components, metabolites, and other mediators of intestinal microflora interacting with the host immune system;
5. Particularly welcome is the exploration of the causal relationship between intestinal microflora/metabolism and diabetes mellitus or tumor immunity through clinical research, animal experiments, and cellular and molecular experiments.
Keywords: gut microbiota
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.