Stroke survivors present with a wide range of neurological, physical, and psychological sequela. Post-stroke epilepsy and vascular dementia is an important complication that is associated with poor clinical outcomes and adversely affects patients’ quality of life. Stroke survivors show a rapid rate of cognitive impairment approximately 3 to 6 months after the stroke. Stroke is the leading cause of dementia worldwide. Advances in acute stroke therapy have contributed to a significant reduction in stroke-induced mortality rates. Increased life expectancy and a growing elderly population have led to a significant increase in the number of stroke survivors.
Cognitive impairment is more common in patients with post-stroke epilepsy than in stroke survivors without post-stroke epilepsy. Previous reports showed approximately 30% of patients with post-stroke epilepsy showed cognitive impairment. Research suggests that mechanisms that contribute to post-stroke epilepsy and vascular dementia may tend to overlap in stroke survivors. Recent reports have implicated amyloid-β deposits as a pathogenetic contributor to both epilepsy and cognitive decline. Amyloid-β deposition is also thought to be affected by vascular conditions and stroke. However, there a few reports about the associations- between anyloid- β, vascular conditions, cognitive impairment and post-stroke epilepsy. In this research topic, we will discuss the mechanism, risk, management of post-stroke epilepsy and vascular dementia in stroke survivors, and address the interaction between post-stroke epilepsy and vascular dementia.
We welcome any types of manuscripts supported by the Journal – comprised of original research article, brief research article, case report, review, mini-review, and meta-analysis, pertaining, but not limited to, the following themes:
• Mechanisms of post-stroke epilepsy and vascular dementia
• Prediction and management of post-stroke epilepsy and vascular dementia
• The association between small vessel diseases, post-stroke epilepsy and vascular dementia
• Management of post-stroke epilepsy and vascular dementia
• The role of Amyloid-β for epilepsy and dementia in stroke survivors
• Neuroimaging assessment of post-stroke epilepsy and vascular dementia
• The impact of stroke on post-stroke epilepsy and vascular dementia
• Novel technologies or discoveries applying the diagnosis or management of post-stroke epilepsy and vascular dementia
Tomotaka Tanaka received speaker's honoraria from Daiichi Sankyo, Eisai, and UCB Japan, and received a research grant from UCB Japan. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Stroke survivors present with a wide range of neurological, physical, and psychological sequela. Post-stroke epilepsy and vascular dementia is an important complication that is associated with poor clinical outcomes and adversely affects patients’ quality of life. Stroke survivors show a rapid rate of cognitive impairment approximately 3 to 6 months after the stroke. Stroke is the leading cause of dementia worldwide. Advances in acute stroke therapy have contributed to a significant reduction in stroke-induced mortality rates. Increased life expectancy and a growing elderly population have led to a significant increase in the number of stroke survivors.
Cognitive impairment is more common in patients with post-stroke epilepsy than in stroke survivors without post-stroke epilepsy. Previous reports showed approximately 30% of patients with post-stroke epilepsy showed cognitive impairment. Research suggests that mechanisms that contribute to post-stroke epilepsy and vascular dementia may tend to overlap in stroke survivors. Recent reports have implicated amyloid-β deposits as a pathogenetic contributor to both epilepsy and cognitive decline. Amyloid-β deposition is also thought to be affected by vascular conditions and stroke. However, there a few reports about the associations- between anyloid- β, vascular conditions, cognitive impairment and post-stroke epilepsy. In this research topic, we will discuss the mechanism, risk, management of post-stroke epilepsy and vascular dementia in stroke survivors, and address the interaction between post-stroke epilepsy and vascular dementia.
We welcome any types of manuscripts supported by the Journal – comprised of original research article, brief research article, case report, review, mini-review, and meta-analysis, pertaining, but not limited to, the following themes:
• Mechanisms of post-stroke epilepsy and vascular dementia
• Prediction and management of post-stroke epilepsy and vascular dementia
• The association between small vessel diseases, post-stroke epilepsy and vascular dementia
• Management of post-stroke epilepsy and vascular dementia
• The role of Amyloid-β for epilepsy and dementia in stroke survivors
• Neuroimaging assessment of post-stroke epilepsy and vascular dementia
• The impact of stroke on post-stroke epilepsy and vascular dementia
• Novel technologies or discoveries applying the diagnosis or management of post-stroke epilepsy and vascular dementia
Tomotaka Tanaka received speaker's honoraria from Daiichi Sankyo, Eisai, and UCB Japan, and received a research grant from UCB Japan. The other Topic Editors declare no competing interests with regard to the Research Topic subject.