About this Research Topic

Manuscript Submission Deadline 15 November 2022

Nutraceuticals are products based on the nutrient content of food, derived from dietary or medicinal plants. Recent reports have suggested the roles of nutraceuticals in the prevention or treatment of human diseases including cancers and neurodegenerative diseases. Due to their ability to modulate different ...

Nutraceuticals are products based on the nutrient content of food, derived from dietary or medicinal plants. Recent reports have suggested the roles of nutraceuticals in the prevention or treatment of human diseases including cancers and neurodegenerative diseases. Due to their ability to modulate different molecular and cellular pathways, nutraceuticals are considered to be beneficial compounds for the prevention and treatment of chronic diseases. Furthermore, the presumed safety, potential nutritional, and chemopreventive activities of nutraceuticals have generated significant global interest in further identifying novel nutraceuticals. According to some epidemiological studies, an appropriate supplement of nutrition can avoid 35% of cancer-caused deaths, and 90% of cancers can be prevented by dietary supplementation. In addition, cumulating evidence strongly supports that the use of nutraceuticals can prevent the onset of neuronal damage and subsequently reduce the progression of neuronal destruction. In general, the neuroprotective effects of nutraceuticals can be attributed to their antioxidative and anti-inflammatory effects.

In recent years, many scientists have focused on the use of nutraceuticals for preventing cancer and neurological diseases through different mechanisms including antioxidant, anti-inflammatory, mitochondrial homeostasis, autophagy regulation, and promoting neurogenesis. However, the detailed molecular mechanisms underlying their protective roles are still largely unknown. Due to the development of conventional technology, we are able to identify more novel nutraceuticals to improve human health. A better understanding of the current or novel nutraceuticals could increase the efficacy of promising nutraceuticals.

We welcome the Original Research based on Clinical Evidence that focuses on the following topics:
· Exploring new methods to isolate novel nutraceuticals;
· Identifying novel nutraceuticals to prevent cancer development or neurodegenerative diseases;
· Exploring the molecular mechanism underlying the roles of nutraceuticals in cancer or neurodegenerative diseases;
· Preclinical/clinical study to identify the pharmacological activities and mechanisms of action of nutraceuticals against cancer development or neurodegenerative diseases supported by animal or clinical data.

Keywords: anti-cancer, anti-neurodegenerative, nutraceutical, molecular mechanism


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